低剂量SPECT/CT对甲状腺良恶性结节鉴别的增益价值

目的 评价低剂量SPECT/CT在鉴别甲状腺良恶性结节中的增益价值。方法 收集触诊/彩色多普勒超声考虑甲状腺结节患者41例，分别行⁹⁹Tc^mO_4-平面显像和低剂量SPECT/CT融合显像，以病理结果为金标准，比较2者诊断效能。结果 低剂量SPECT/CT融合显像诊断甲状腺结节良恶性的灵敏度、特异度、准确率及受试者工作特征（ROC）曲线下面积（AUC）分别为61.90%、53.33%、63.41%和0.64；均高于^99mTcO_4-平面显像的19.05%、45.00%、31.70%和0.32（P均<0.05）。结论 低剂量SPECT/CT对恶性甲状腺结节的诊断效能优于⁹⁹Tc^mO_4-平面显像。

Gain value of low-dose SPECT/CT in differential diagnosis of benign and malignant thyroid nodules

Objective To evaluate the gain value of low-dose SPECT/CT in differential diagnosis of benign and malignant thyroid nodules. Methods Totally 41 patients with thyroid nodule considered by palpation/color Doppler ultrasonography were prospectively collected. ⁹⁹Tc^mO_4- plane imaging, low-dose SPECT/CT fusion imaging were performed, respectively. Results The sensitivity, specificity, accuracy and area under the receiver operating characteristic (ROC) curve (AUC) of low-dose SPECT/CT fusion imaging in differential diagnosis of benign and malignant thyroid nodules were 61.90%, 53.33%, 63.41% and 0.64, respectively; which were higher than those of planar imaging of 19.05%, 45.00%, 31.70% and 0.32 (all P<0.05). Conclusion Low-dose SPECT/CT is better than ⁹⁹Tc^mO_4- planar imaging in diagnosis of malignant thyroid nodule.