| 定量型声辐射力脉冲弹性成像评价慢性心力衰竭患者肝脏弹性 |
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| 引用本文： | 杨敬武,刘强,刁海霞,罗玉君,张立霞,郭晓扬,丁康. 定量型声辐射力脉冲弹性成像评价慢性心力衰竭患者肝脏弹性[J]. 中国医学影像技术, 2019, 35(7): 1049-1052 |
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| 作者姓名： | 杨敬武 刘强 刁海霞 罗玉君 张立霞 郭晓扬 丁康 |
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| 作者单位： | 南方医科大学第二临床医学院, 广东 广州 510280,中国人民解放军第三○五医院超声科, 北京 100017,南方医科大学第二临床医学院, 广东 广州 510280,中国人民解放军第三○五医院超声科, 北京 100017,中国人民解放军第三○五医院超声科, 北京 100017,中国人民解放军第三○五医院超声科, 北京 100017,南方医科大学第二临床医学院, 广东 广州 510280;中国人民解放军第三○五医院超声科, 北京 100017 |
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| 基金项目： | 中国人民解放军第三○五医院院内基金（17YZ06）。 |
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| 摘 要： | 目的 探讨定量型声辐射力脉冲弹性成像（ARFI）评估慢性心力衰竭（简称心衰）患者肝脏弹性的应用价值。方法 对30例左心衰患者（左心衰组）、30例右心衰患者（右心衰组）及30名健康志愿者（对照组）行常规超声检查及血液生化指标检测，并以定量型ARFI检测肝脏杨氏模量值。分析慢性心衰患者肝脏杨氏模量值与生化指标、下腔静脉内径、肝静脉内径及肝右叶最大斜径的相关性。结果 左心衰组、右心衰组肝脏杨氏模量值均高于对照组（P均<0.05），且右心衰组高于左心衰组（P<0.05）。心衰患者肝脏杨氏模量值与脑钠肽、总胆红素、γ-谷氨酰基转移酶、碱性磷酸酶、下腔静脉内径、肝左静脉内径、肝中静脉内径及肝右静脉内径均呈正相关（r=0.325、0.382、0.355、0.379、0.451、0.445、0.395、0.645，P均<0.05），与左心室射血分数、肝右叶最大斜径无明显相关（P均>0.05）。结论 定量型ARFI可用于评估慢性心衰患者肝脏弹性，且肝脏弹性与心衰严重程度相关。
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| 关 键 词： | 心力衰竭 肝 弹性成像技术 超声检查 |
| 收稿时间： | 2018-11-19 |
| 修稿时间： | 2019-06-06 |
Quantitative acoustic radiation force impulse imaging in evaluation on elasticity of liver in patients with chronic heart failure |
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| YANG Jingwu,LIU Qiang,DIAO Haixi,LUO Yujun,ZHANG Lixi,GUO Xiaoyang and DING Kang. Quantitative acoustic radiation force impulse imaging in evaluation on elasticity of liver in patients with chronic heart failure[J]. Chinese Journal of Medical Imaging Technology, 2019, 35(7): 1049-1052 |
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| Authors: | YANG Jingwu LIU Qiang DIAO Haixi LUO Yujun ZHANG Lixi GUO Xiaoyang DING Kang |
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| Affiliation: | The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510280, China,Department of Ultrasound, the 305 Hospital of People''s Liberation Army, Beijing 100017, China,The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510280, China,Department of Ultrasound, the 305 Hospital of People''s Liberation Army, Beijing 100017, China,Department of Ultrasound, the 305 Hospital of People''s Liberation Army, Beijing 100017, China,Department of Ultrasound, the 305 Hospital of People''s Liberation Army, Beijing 100017, China and The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510280, China;Department of Ultrasound, the 305 Hospital of People''s Liberation Army, Beijing 100017, China |
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| Abstract: | Objective To explore the value of quantitative acoustic radiation force impulse (ARFI) imaging in evaluation of liver elasticity in patients with chronic heart failure (HF). Methods Totally 30 left HF patients (LHF group), 30 right HF patients (RHF group) and 30 healthy volunteers (control group) underwent routine ultrasound examination and biochemical examination, and then Young''s modulus value of liver was detected using quantitative ARFI imaging. Correlations between Young''s modulus value of liver and biochemical indexes, diameter of inferior vena cava, diameter of liver vein and oblique diameter of right lobe of liver were analyzed in patients with chronic HF. Results Young''s modulus value of liver in LHF group and RHF group were higher than that in control group (both P<0.05), and in RHF group was higher than in LHF group (P<0.05). Young''s modulus value of liver in chronic HF patients positively correlated with brain natriuretic peptide, total bilirubin, gamma glutamyl transferase, alkaline phosphatase, diameter of inferior vena cava, diameter of left liver vein, diameter of middle hepatic vein and diameter of right liver vein (r=0.325, 0.382, 0.355, 0.379, 0.451, 0.445, 0.395, 0.645, all P<0.05), while no correlation was noticed between Young''s modulus of liver and ejection fraction of left ventricle nor oblique diameter of right lobe of liver (all P>0.05). Conclusion Quantitative ARFI imaging can be used to estimate the elasticity of liver in chronic HF patients. Liver elasticity is associated with the severity of heart failure. |
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| Keywords: | heart failure liver elasticity imaging techniques ultrasonography |
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