| 18F-FDG PET脑显像和多巴胺能神经元突触功能PET脑显像研究帕金森病进展 |
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| 引用本文： | 宋天彬,卢洁. 18F-FDG PET脑显像和多巴胺能神经元突触功能PET脑显像研究帕金森病进展[J]. 中国医学影像技术, 2019, 35(12): 1884-1888 |
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| 作者姓名： | 宋天彬 卢洁 |
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| 作者单位： | 首都医科大学宣武医院核医学科, 北京 100053,首都医科大学宣武医院核医学科, 北京 100053;首都医科大学宣武医院放射科, 北京 100053;磁共振成像脑信息学北京市重点实验室, 北京 100053 |
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| 基金项目： | 国家自然科学基金面上项目（81671662）、北京市医管局人才培养计划"登峰"项目（DFL20180802）。 |
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| 摘 要： | 帕金森病（PD）是常见神经退行性疾病,PET对早期鉴别、诊断和评价PD具有特别优势,主要示踪剂为反映葡萄糖代谢的18F-FDG和反映纹状体多巴胺能神经元突触功能的靶向示踪剂。本文就18F-FDG PET脑显像和多巴胺能神经元突触功能PET脑显像应用于PD研究现状和进展进行综述。
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| 关 键 词： | 帕金森病 氟脱氧葡萄糖F18 多巴胺 正电子发射断层显像 |
| 收稿时间： | 2019-03-11 |
| 修稿时间： | 2019-10-20 |
Research development of 18F-FDG and dopaminergic neuron function targeting PET brain imaging on evaluation of Parkinson disease |
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| SONG Tianbin and LU Jie. Research development of 18F-FDG and dopaminergic neuron function targeting PET brain imaging on evaluation of Parkinson disease[J]. Chinese Journal of Medical Imaging Technology, 2019, 35(12): 1884-1888 |
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| Authors: | SONG Tianbin and LU Jie |
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| Affiliation: | Department of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China and Department of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China |
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| Abstract: | Parkinson disease (PD) is a common neurodegenerative disease. PET has special advantages in early identification, diagnosis and evaluation of PD. The main PET tracers contain 18F-FDG and dopaminergic neuron function targeting imaging tracers. The research status and progresses of 18F-FDG PET brain imaging and dopaminergic neuron function targeting imaging on evaluation of PD were reviewed in this article. |
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| Keywords: | Parkinson disease fludeoxyglucose F18 dopamine positron-emission tomography |
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