卵巢癌脾脏转移瘤18F-FDG PET/CT表现

目的 观察卵巢癌脾脏转移瘤的¹⁸F-FDG PET/CT表现。方法 回顾性分析经病理及临床随访证实的21例卵巢癌脾脏转移瘤患者的¹⁸F-FDG PET/CT表现，分析病灶最大标准摄取值（SUV_max）与最大径的相关性。结果 21例中，17例单发，4例多发，共28个病灶。13个病灶¹⁸F-FDG PET/CT表现为类圆形低密度影，其中9个病灶边界清晰，4个病灶边界不清；4个病灶密度不均匀，内见坏死、囊变，余9个病灶密度均匀。15个病灶表现为类圆形等密度影，边界不清，密度均匀。28个病灶均呈¹⁸F-FDG高摄取，其中21个病灶¹⁸F-FDG摄取均匀，7个病灶¹⁸F-FDG摄取不均匀。卵巢癌脾脏转移瘤的SUV_max为8.04±3.92，最大径为（2.23±1.02） cm，SUV_max与最大径呈正相关（r=0.687，P<0.001）。21例中，5例肿瘤仅累及脾脏；16例累及其他部位。结论 卵巢癌脾脏转移瘤的¹⁸F-FDG PET/CT表现具有一定特征性。

18F-FDG PET/CT manifestations of splenic metastasis of ovarian cancer

Objective To observe ¹⁸F-FDG PET/CT manifestations of splenic metastasis of ovarian cancer.Methods ¹⁸F-FDG PET/CT imaging features and clinical data of splenic metastases of ovarian cancer in 21 patients were retrospectively analyzed. The correlation between maximum standardized uptake value (SUV_max) and the maximum diameter of lesion was analyzed.Results Among 21 patients (28 lesions), single lesion was found in 17 patients and multiple lesions were found in 4 patients. Thirteen lesions were found as round and low density masses, among which heterogeneous density with necrotic and cystic degeneration were detected in 4 lesions, while uniform density was found in 9 lesions. Fifteen lesions were found as round and homogeneous density masses with obscure boundary and uniform densities. High ¹⁸F-FDG uptake was noticed in all 28 lesions, uniform in 21 lesions and heterogeneous in 7 lesions. The SUV_max of splenic metastases was 8.04±3.92, and the maximal diameter of these 28 lesions was (2.23±1.02)cm. The SUV_max was higher positively correlated with maximal diameter of splenic metastases (r=0.687, P<0.001). Among 21 patients, single spleen involvement was found in 5 patients, while whole body multi-involvement were found in 16 patients.Conclusion Splenic metastases of ovarian cancer have certain ¹⁸F-FDG PET/CT characteristics.