超声引导下介入治疗莫顿神经瘤

目的 探讨超声引导下介入治疗莫顿神经瘤的临床效果。方法 将36例莫顿神经瘤患者随机分为观察组（n=19）和对照组（n=17例）。对观察组进行超声引导下介入治疗，对照组给予传统封闭治疗。观察2组患者治疗过程中是否出现血管、肌腱损伤，治疗后8周内是否出现感染等并发症。分别于治疗前及治疗后4、8周进行疼痛数字评价量表（NRS）评分；于治疗前及治疗后8周比较肿瘤最大径。结果 2组患者治疗过程中均未见血管、肌腱损伤等并发症。对照组6例治疗后8周内出现局部感染，经对症治疗后缓解。观察组患者治疗后4、8周NRS评分均较治疗前降低（P均<0.01）；对照组患者治疗后4周NRS评分较治疗前降低（P<0.01），而治疗后8周与治疗前及治疗后4周差异均无统计学意义（P均>0.05）。治疗前及治疗后4周，2组患者NRS评分差异均无统计学意义（P均>0.05）；治疗后8周，观察组患者NRS评分较对照组降低（P<0.001）。治疗前及治疗后8周2组肿瘤最大径差异均无统计学意义（P均>0.05）。结论 超声引导下介入治疗莫顿神经瘤安全、有效。

Clinical efficacy of ultrasound-guided interventional therapy for Morton neuroma

Objective To investigate the clinical efficacy of ultrasound-guided interventional therapy for Morton neuroma. Methods All 36 patients with Morton neuroma were randomly divided into observation group (n=19) and control group (n=17). The patients of observation group were given ultrasound-guided interventional therapy, while the patients of control group were treated with traditional occlusive therapy. Vascular and tendon injuries during therapy, infection and other complications during 8 weeks after treatment were observed. Numerical rating scale (NRS) were assessed before treatment and 4 weeks and 8 weeks after treatment, and the maximum diameter of tumor before treatment and 8 weeks after treatment were compared. Results No complications such as vascular and tendon injuries were observed in 2 groups during treatment. Six patients in control group had local infection during 8 weeks after treatment, which were relieved after symptomatic treatment. In observation group, NRS scores decreased obviously in 4 weeks and 8 weeks after treatment compared with before treatment (both P<0.01). Compared with that before treatment, NRS score of 4 weeks after treatment decreased in control group (P<0.01), while no significant difference was found between 8 weeks after treatment and before treatment (P>0.05), as well as between 8 weeks and 4 weeks after treatment (P>0.05). There was no significant difference of NRS scores before treatment and 4 weeks after treatment in both 2 groups (both P>0.05), while NRS score of observation group decreased compared with control group 8 weeks after treatment (P<0.001). The differences of the maximum diameter of tumors before treatment and 8 weeks after treatment were not statistically significant between 2 groups (both P>0.05). Conclusion Ultrasound-guided intervention is efficacy and safety in treatment of Morton neuroma.