常规超声联合声触诊组织量化成像技术对乳腺病变的鉴别诊断价值

目的:探讨常规超声联合声触诊组织量化成像技术(virtual touch tissue imaging quantification,VTIQ)对乳腺良恶性病变的鉴别诊断价值。方法:采用常规超声和VTIQ技术对2019年4月至2019年9月复旦大学附属中山医院厦门医院62例乳腺病灶进行检查,常规超声观察病灶回声、形态、有无点状钙化、穿支血流等特征,并用VTIQ技术测量病灶横向剪切波速度(shear wave velocity,SWV)的最大值SWV_(max)及平均值SWV_(mean),以病理结果为金标准,ROC曲线计算SWV_(max)及SWV_(mean)的截断值,比较常规超声及常规超声结合VITQ的诊断效能。结果:62例病灶中,41例为良性肿瘤,21例为恶性肿瘤。VTIQ的SWV_(max)及SWV_(mean)截断点分别为5.4 m/s和4.2 m/s,SWV_(max)和SWV_(mean)诊断敏感度、特异度分别为72.0%、92.1%和86.0%、79.0%。常规超声和常规超声结合VTIQ诊断敏感度、特异度、Youden指数、阳性预测值、阴性预测值分别为68%、74%、42%、72%、83%和77%、97%、74%、86%、92%,差异具有统计学意义(P0.05)。结论:常规超声联合VTIQ有助于提高乳腺良恶性病变的诊断能力,值得进一步推广。

Clinical value of conventional ultrasound combined with virtual touch tissue imaging quantification (VTIQ) for breast lesions

[Abstract] Objective: To explore the value of conventional ultrasound combined with Virtual Touch Tissue Imaging Quantification (VTIQ) in differential diagnosis of benign and malignant breast lesions. Methods: Sixty-two breast lesions were examined by conventional ultrasound and VTIQ technique. The echo, morphology, punctate calcification and perforator blood flow were observed by conventional ultrasound. The SWVmax and the SWVmean of transverse shear wave velocity (SWV) were measured by VTIQ technique. The cut-off values of SWVmax and SWVmean were calculated by ROC curve based on pathological results. Diagnostic efficacy of conventional ultrasound combined with VITQ was compared with conventional ultrasound for breast lesions diagnosis. Results: Among 62 cases, 41 cases were benign tumors and 21 cases were malignant tumors. The cut-off points of SWVmax and SWVmean of VTIQ were 4.2m/s and 5.4m/s,respectively. The sensitivity and specificity of SWVmax and SWVmean were 86%, 79% and 73%, 92%. The sensitivity, specificity, accuracy, positive and negative predictive values of conventional ultrasound and conventional ultrasound combined with VTIQ were 68%,74%,42%,72%,83% vs 77%, 97%, 74%, 86%, 92% with significant difference(P < 0.05). Conclusion: Conventional ultrasound Combined with VTIQ is helpful to improve the diagnostic ability of conventional ultrasound for breast lesions, which is worthy of further promotion.[Key words] Breast lesions; Conventional ultrasound; VTIQ; SWV