声触诊组织成像定量技术评价正常成人睾丸生精功能

目的 采用声触诊组织成像定量（VTIQ）技术测量正常成人睾丸剪切波速度（SWV），分析影响睾丸弹性硬度的主要因素，探讨其评价男性睾丸生精功能的价值。方法 招募200名正常成年男性志愿者行睾丸常规超声检查，测量双侧睾丸体积。以VTIQ技术测量双侧睾丸上极、中份、下极的SWV，比较双侧睾丸、不同年龄组睾丸SWV差异，并与年龄、睾丸体积和精子活动率和精子密度进行相关性分析。结果 200名正常成年男性左右侧睾丸SWV均为（1.23±0.18）m/s，左右侧差异无统计学意义（t=-0.376，P=0.710）。21~30岁组、31~40岁组、41~50岁与51~60岁组间双侧睾丸SWV值总体差异均有统计学意义（P均<0.001）。睾丸SWV与年龄呈正相关（r=0.454，P<0.001），与睾丸体积、精子活动率和精子密度分别呈负相关（r=-0.649、-0.668、-0.675，P均<0.001）。结论 VTIQ技术可定量测量睾丸组织硬度，有望用于初步评估睾丸生精功能。

Virtual touch tissue imaging quantitative evaluation on normal adult testicular spermatogenesis

Objective To measure the shear wave velocity (SWV) of normal adult testis using virtual touch tissue imaging quantification(VTIQ), and to analyze the main impact factors of testicular stiffness and the value of VTIQ in evaluation of testicular spermatogenesis. Methods Totally 200 normal adult male volunteers were recruited and underwent routine testicular ultrasonography for the measurement of bilateral testicular volume. VTIQ technique was used to measure SWV of the upper, middle and lower poles of the bilateral testis. The differences of SWV in bilateral testis and testis of different age groups were compared. The correlation of SWV with age, testicular volume and sperm motility and density was analyzed. Results SWV of both the left and right lateral testis of 200 normal adult males were (1.23±0.18)m/s, and no statistically significant difference was found (t=-0.376, P=0.710). There were significant differences of SWV among the 21-30 years old group, 31-40 years old group, 41-50 years old and 51-60 years old group (all P<0.001). Testicular SWV was positively correlated with age (r=0.454, P<0.001) and negatively correlated with testicular volume, sperm motility and density (r=-0.649, -0.668, -0.675, all P<0.001). Conclusion VTIQ technique can quantitatively measure testicular tissue hardness, which may be used to initially evaluate testicular spermatogenesis.