| 中药活性成分防治脓毒症的研究进展 |
| |
| 引用本文： | 薛漓轩,周钱留,张媛媛,寇俊萍. 中药活性成分防治脓毒症的研究进展[J]. 药学研究, 2019, 38(6): 311-317,325 |
| |
| 作者姓名： | 薛漓轩 周钱留 张媛媛 寇俊萍 |
| |
| 作者单位： | 1.中国药科大学中药学院中药药理与中医药系，江苏 南京 211198；2.江苏省中药评价与转换重点实验室，江苏 南京 211198,1.中国药科大学中药学院中药药理与中医药系，江苏 南京 211198；2.江苏省中药评价与转换重点实验室，江苏 南京 211198,1.中国药科大学中药学院中药药理与中医药系，江苏 南京 211198；2.江苏省中药评价与转换重点实验室，江苏 南京 211198,1.中国药科大学中药学院中药药理与中医药系，江苏 南京 211198；2.江苏省中药评价与转换重点实验室，江苏 南京 211198 |
| |
| 基金项目： | 国家自然科学基金项目（No.81773971） |
| |
| 摘 要： | 脓毒症(sepsis)是感染引起宿主反应失调所致的致命性器官功能障碍，其死亡率居高不下，严重威胁人类生命安全，治疗脓毒症的药物研究一直是全球研究的热点。近年来中药有效成分在治疗脓毒症方面取得许多进展，本文拟从抑制脓毒症期间的炎症反应、抑制氧化应激、调节免疫反应、调节细胞死亡、调节内皮屏障功能5个方面对近3年来发表在英文期刊上的中药活性成分防治脓毒症的机制进展予以综述，以期为研发防治脓毒症的新药提供参考依据和线索。
|
| 关 键 词： | 中药；活性成分；脓毒症；多器官功能障碍；研究进展 |
Advances of active components of traditional Chinese medicines in the prevention and treatment of sepsis |
| |
| XUE Lixuan,ZHOU Qianliu,ZHANG Yuanyuan and KOU Junping. Advances of active components of traditional Chinese medicines in the prevention and treatment of sepsis[J]. Journal of Pharmaceutical Research, 2019, 38(6): 311-317,325 |
| |
| Authors: | XUE Lixuan ZHOU Qianliu ZHANG Yuanyuan KOU Junping |
| |
| Affiliation: | 1.Department of Pharmacology of Chinese Material Medical, School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 211198,China;2.Jiangsu Key Laboratory of Traditional Chinese Medicine Evaluation and Translational Research,Nanjing 211198,China,1.Department of Pharmacology of Chinese Material Medical, School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 211198,China;2.Jiangsu Key Laboratory of Traditional Chinese Medicine Evaluation and Translational Research,Nanjing 211198,China,1.Department of Pharmacology of Chinese Material Medical, School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 211198,China;2.Jiangsu Key Laboratory of Traditional Chinese Medicine Evaluation and Translational Research,Nanjing 211198,China and 1.Department of Pharmacology of Chinese Material Medical, School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 211198,China;2.Jiangsu Key Laboratory of Traditional Chinese Medicine Evaluation and Translational Research,Nanjing 211198,China |
| |
| Abstract: | |
| |
| Keywords: | Traditional Chinese medicines Active components Sepsis Multiple organ dysfunction Research progress |
|
| 点击此处可从《药学研究》浏览原始摘要信息 |
|
点击此处可从《药学研究》下载免费的PDF全文 |
|
