| 替罗非班对急性ST段抬高型心肌梗死直接经皮冠状动脉介入术后心肌灌注和临床预后的影响 |
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| 引用本文： | 文治勇,刘超,黎玉环.替罗非班对急性ST段抬高型心肌梗死直接经皮冠状动脉介入术后心肌灌注和临床预后的影响[J].当代医学,2010,16(5):99-100. |
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| 作者姓名： | 文治勇 刘超 黎玉环 |
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| 作者单位： | 湖北443000,宜昌市第二人民医院心内科 |
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| 摘 要： | 目的观察替罗非班对ST段抬高型心肌梗死（STEMI）患者急诊经皮冠状动脉介入术（PCI）后心肌灌注和临床预后的影响。方法选择75例符合直接PCI的急性STEMI患者,随机分为替罗非班实验组（38例）和对照组（37例）,实验组在PCI基础上加替罗非班、对照组直接PCI,观察两组术后心肌缺血再灌注损伤,住院期间主要心血管事件（MACE）及临床预后。结果治疗组在PCI术前后冠脉TIMI以及TMP分级、心电图ST段回落、7d后左心室射血分数（LVEF）、主要心血管事件MACE发生率等方面显著优于对照组,术后肌钙蛋白I（cTnI）峰值、住院天数、出血并发症、住院期间主要心血管事件（MACE）两组之间无差异。结论对于急性STEMI行PCI前应用替罗非班可更有效的改善冠脉血流及临床预后,方法安全。
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| 关 键 词： | 心肌梗死 心肌灌注 冠状动脉介入术 替罗非班 |
The effect of Tirofiban in myocardial perfusion and clinical prognosis of patients with acute ST-segment elevation myocardial infarctionafter percutaneous coronaryintervention |
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| WEN Zhi-yong,LIU Chao,LI Yu-huan.The effect of Tirofiban in myocardial perfusion and clinical prognosis of patients with acute ST-segment elevation myocardial infarctionafter percutaneous coronaryintervention[J].Contemporary Medicine,2010,16(5):99-100. |
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| Authors: | WEN Zhi-yong LIU Chao LI Yu-huan |
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| Institution: | WEN Zhi-yong,LIU Chao,LI Yu-huan Department of Orthopaedics,Second People Hospital of Yichang City,Yichang 443000,China |
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| Abstract: | Objective To observe the effect of tirofiban in myocardial perfusion and clinical prognosis of patients with acute ST-segment elevation myocardial infarction(STEMI) after percutaneous coronary intervention(PCI).Methods 75 cases consistent with a direct PCI for acute STEMI were randomly divided into experimental tirofiban group(38 cases) and control group(37 cases),the experimental group based on the PCI plus tirofiban and the control group directly PCI.It was observed of myocardial ischemia-reperfusion inju... |
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| Keywords: | Myocardial infarction myocardial perfusion coronary intervention tirofiban |
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