Culture-proven cytomegalovirus retinitis in a homosexual man with the acquired immunodeficiency syndrome |
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Authors: | D M Bachman M M Rodrigues F C Chu S E Straus D G Cogan A M Macher |
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Affiliation: | 1. National Eye Institute, The Laboratory of Clinical Investigation, National Institutes of Allergy and Infectious Diseases, and the Microbiology Service, Department of Clinical Pathology, The National Institutes of Health, Bethesda, Maryland. |
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Abstract: | A 35-year-old homosexual man with cytomegalovirus viremia developed retinitis. He also had a new syndrome consisting of a persistent T-lymphocyte deficit, pneumocystis pneumonia, recurrent Candida albicans esophagitis, skin ulcerations caused by herpes simplex virus, Type 2, disseminated Mycobacterium avium-intracellulare infection, and molluscum contagiosum. Histopathologic examination revealed bilateral necrotizing retinitis with virions in retinal, choroidal, and optic nerve tissues. Postmortem cultures of retina and vitreous were positive for cytomegalovirus. |
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Keywords: | cytomegalovirus homosexual immunosuppression retinitis |
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