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Culture-proven cytomegalovirus retinitis in a homosexual man with the acquired immunodeficiency syndrome
Authors:D M Bachman  M M Rodrigues  F C Chu  S E Straus  D G Cogan  A M Macher
Affiliation:1. National Eye Institute, The Laboratory of Clinical Investigation, National Institutes of Allergy and Infectious Diseases, and the Microbiology Service, Department of Clinical Pathology, The National Institutes of Health, Bethesda, Maryland.
Abstract:A 35-year-old homosexual man with cytomegalovirus viremia developed retinitis. He also had a new syndrome consisting of a persistent T-lymphocyte deficit, pneumocystis pneumonia, recurrent Candida albicans esophagitis, skin ulcerations caused by herpes simplex virus, Type 2, disseminated Mycobacterium avium-intracellulare infection, and molluscum contagiosum. Histopathologic examination revealed bilateral necrotizing retinitis with virions in retinal, choroidal, and optic nerve tissues. Postmortem cultures of retina and vitreous were positive for cytomegalovirus.
Keywords:cytomegalovirus  homosexual  immunosuppression  retinitis
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