乙肝病毒携带产妇HBIG应用及不同喂养方式对婴儿的影响

目的：探讨乙肝病毒携带产妇的母乳喂养问题。方法：将134例HBsAg阳性产妇分为2组，HBIG组(A组)66例，于孕28、32、36周分别注射HBIG 200IU，非HBIG组(B组)68例不用药。分别检测孕妇外周血、初乳和婴儿0、6个月外周血中乙肝两对半和HBV-DNA。结果：HBIG组与非HBIG组初乳中HBsAg阳性率差别无显著性，初乳中不论HBsAg阳性或阴性，婴儿行母乳喂养或人工喂养6月龄HBsAb阳性率差异无显著性。结论：HBsAg携带孕妇婴儿进行母乳喂养和人工喂养6月龄婴儿外周血HBsAb阳性率差异无显著性。

The application of HBIG to parturients women carring HBsAg and the effect of different feeding way to infants

Objective To explore the breast feed ing of parturients women carring HBsAg. Methods From March 2001 to March 2003, 134 parturients women carring HBsAg were divided into two groups. Group A (n=66), which HBIG 200 IU was given monthly in late pregnancy; Group B (n=68), which abtained onl y common antenatal care. The pregnant women's vein blood, colostrums and the v ein blood of infants (age=0, 6-month old) underwent an examination of HBV immu nological markers and HBV-DNA. Results The HBsAg positive rate in colostrums of group A and that of group B had no significant difference. For 6 months infants, the HBsAb positive rate of infant blood had no significant difference between breast - feeding and artificial-feeding no matter positive or negative the HBsAg in colo s trums. Conclusion As the infants of pregnant women carring HBsAg were 6 months old, the HBsAb positive rate of infant blood had no significant difference betw een breast-feeding and artificial-feeding.