门诊肥胖儿童代谢综合征状况分析

目的 分析门诊肥胖儿童代谢综合征(MS)的发病情况.方法 选择113名肥胖病营养专科门诊就诊的7-14岁肥胖儿童为病例组,以同期366名7-14岁健康学生为对照组,测量两组的身高、体质量、腰围、臀围、血压、肝脏超声,并检测空腹血糖、空腹胰岛素、血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)等相关生化指标,诊断MS的发病率.采用HOMA-IR的四分位数分割点来定义有无胰岛素抵抗.结果 病例组与对照组的年龄和性别比无统计学差异(P>0.05),而体质量、体质量指数(BMI)、腰围、臀围、腰臀比(WHR)、收缩压(SBP)、舒张压(DBP)、空腹血糖、空腹胰岛素、HOMA 指数和TG均明显高于对照组(P<0.01).对照组HOMA指数第75位百分位值为3.28,以此为切点将病例组分胰岛素抵抗组和非胰岛素抵抗组.病例组中胰岛素抵抗儿童体质量、BMI、腰围、TG均明显高于非胰岛素抵抗组儿童(P<0.05);病例组中有51例(45.1%)儿童发生MS.胰岛素抵抗组儿童MS发病率高于非胰岛素抵抗组儿童(50.O%us 21.1%)(P<0.05).结论 超重和肥胖儿童MS发病率较高;MS发生与胰岛素抵抗明显相关.

Analysis of metabolic syndrome among obese children in clinics

Objective To investigate the incidence of metabolic syndrome among obese children in clinics.Methods One hundred and thirteen obese children aged 7 to 14 years were selected from clinics of nutrition(case group),and another 366 healthy students aged 7 to 14 years were served as controls.Height,body weight,waist circumference,hip circumference,blood pressure and liver ultrasound were measured,related biochemical parameters such as fasting blood glucose,fasting insulin,serum total cholesterol,triglyceride(TG)...