| 硒酵母对阿尔茨海默病患者血清一氧化氮,超敏C反应蛋白的影响# |
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| 引用本文： | 徐进亮,李亮,王建华,毕建波,曲忠森. 硒酵母对阿尔茨海默病患者血清一氧化氮,超敏C反应蛋白的影响#[J]. 中国医药导刊, 2012, 14(1): 83-84 |
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| 作者姓名： | 徐进亮 李亮 王建华 毕建波 曲忠森 |
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| 作者单位： | 1. 潍坊医学院附属青岛市胶州中心医院,青岛,266300
2. 上海交通大学附属第六人民医院,上海,200233 |
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| 摘 要： | 目的:观察硒酵母对阿尔茨海默病患者一氧化氮及超敏C反应蛋白的影响。方法:将60例阿尔茨海默病患者随机分为阿尔茨海默病组(20例),治疗组(20例)和对照组(20例),治疗组和对照基础治疗相同,治疗组在对照组基础治疗上加服硒酵母胶囊,用硝酸还原法及免疫散射比浊法检测血清NO及hs-CRP的水平。结果:与对照组比较,治疗组升高NO(P<0.05),降低hs-CRP水平更明显(P<0.05)。结论:硒酵母可能对AD患者炎症反应诱导的血管内皮功能损伤有潜在的修复作用。
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| 关 键 词： | 硒酵母 阿尔茨海默病 一氧化氮 C-反应蛋白 |
Effects of Selenium Yeast on Serum Nitric Oxide and High-sensitivity C-reactive Protein in Patients with Alzheimer Disease |
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| Affiliation: | Xu Jinliang,Li Liang,Wang Jianhua,et al.(Affiliated Jiaozhou Center Hospital of Weifang Medical College,Shandong,Jiaozhou 266300,China) |
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| Abstract: | Objective:To observe the effcts of selenium yeast on nitric oxide and high-sensitivity C-reactive protein in patients with Alzheimer disease(AD).Methods:The levels of nitric oxide and high-sensitivity C-reactive protein were measured in AD group,control group,and treatment group.Results:As compared with the control group,the level of NO was decreased and the level of hs-CRP was increased in treatment group(P<0.05,P<0.05).Conclusion:Selenium yeast might recovery the vascular endothelial dysfunction induced by chronic inflammation in patients with AD. |
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| Keywords: | Selenium yeast Alzheimer disease Nitric oxide C-reactive protein |
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