| 正交设计优选葛根降糖颗粒的最佳提取工艺 |
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| 引用本文： | 徐凤娟,张振秋,冯勇. 正交设计优选葛根降糖颗粒的最佳提取工艺[J]. 辽宁中医杂志, 2007, 34(11): 1615-1616 |
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| 作者姓名： | 徐凤娟 张振秋 冯勇 |
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| 作者单位： | 辽宁中医药大学药学院,辽宁,大连,116600 |
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| 摘 要： | 目的:优选葛根降糖颗粒的最佳提取工艺。方法:采用HPLC法,以葛根素的提取率为评价指标,以正交试验法L9(3)4优选提取工艺参数。结果:提取次数为主要影响因素,其次是溶媒量和乙醇浓度。确定最佳工艺为用60%乙醇,加15倍量,提取3h,提取2次。结论:优选的提取工艺稳定,可行。
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| 关 键 词： | 正交设计 葛根素 最佳提取工艺 高效液相色谱 |
| 文章编号： | 1000-1719（2007）11-1615-02 |
| 修稿时间： | 2007-06-14 |
Orthogonal Design to Optimize the Extraction Technics of Pueraria Jiangtang Granule |
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| XU Feng-juan,ZHANG Zhen-qiu,FENG Yong. Orthogonal Design to Optimize the Extraction Technics of Pueraria Jiangtang Granule[J]. Liaoning Journal of Traditional Chinese Medicine, 2007, 34(11): 1615-1616 |
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| Authors: | XU Feng-juan ZHANG Zhen-qiu FENG Yong |
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| Affiliation: | Pharmacology School ,Liaoning University of Traditional Chinese Medicine,Dalian 116600 ,Liaoning, China |
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| Abstract: | Objective:The optimize the extraction technics of Pueraria Jiangtang Granule.Methods:Uses the HPLC,take the Puerarin extraction rate as the appraisal target,by orthogonal testing method L9(3)4 optimal extraction craft parameter.Results: The extraction number of times for the major effect factor,next is the solvent quantity and the mellow density.The determination best craft for uses the concentration of alcohol was 60%,volume of alcohol was 15 times raw herb,and the herb was extractde 2 times,withdraws for 3 hours.Conclusion: The optimal extraction craft is stable,feasible. |
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| Keywords: | orthogonal design puerarin the best process HPLC |
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