Neuroimaging findings of postnatally acquired Zika virus infection: a pictorial essay |
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| Authors: | Mohammad Zare Mehrjardi Guillaume Carteaux Andrea Poretti Morteza Sanei Taheri Sonia Bermudez Heron Werner Luiz Celso Hygino da Cruz Jr. |
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| Affiliation: | 1.Department of Radiology,Shohada Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences,Tehran,Iran;2.Section of Neuroimaging, Division of Clinical Research, Climax Radiology Education Foundation,Tehran,Iran;3.Assistance Publique-H?pitaux de Paris, CHU Henri Mondor, DHU A-TVB, Service de Réanimation Médicale,Créteil,France;4.Université Paris Est Créteil, Faculté de Médecine de Créteil, Groupe de recherché clinique CARMAS,Créteil,France;5.Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science,The Johns Hopkins University School of Medicine,Baltimore,USA;6.Section of Neuroradiology,Department of Diagnostic Imaging, Fundacion Santa Fe de Bogotá University Hospital,Bogotá,Colombia;7.Department of Radiology,Clínica de Diagnóstico por Imagem (CDPI),Rio De Janeiro,Brazil;8.Department of Radiology,CDPI/DASA, Américas Medical City,Rio De Janeiro,Brazil |
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| Abstract: | Zika virus (ZIKV) is a mosquito-borne arbovirus from the Flaviviridae family, first discovered in 1947. There has been no report of severe complications caused by this virus in humans until recently. However, it is confirmed now that prenatally acquired ZIKV infection may cause severe congenital brain abnormalities in the infected fetuses. In addition, there has been an increasing number of reports during recent years about the causal relationship between postnatally acquired ZIKV infection and severe neurologic complications (mostly immune-mediated ones). Hence, ZIKV should not be considered as benign as it was initially thought, but it might be seen as a serious global threat to human health that may severely affect not only fetuses. In this pictorial essay, we aim to describe and illustrate the currently recognized spectrum of neuroimaging findings in postnatally acquired ZIKV infection. Although neurologic complications do not frequently occur in postnatal ZIKV infection, it is important to be aware of them because they may cause high morbidity and mortality in the affected patients. In addition to clinical and laboratory findings, neuroimaging may help in the diagnostic work-up to make the correct diagnosis, determine the extent of the disease, and follow the clinical course. |
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