| 半量GnRH拮抗剂方案对IVF-ET控制性超促排卵(COH)的临床效果 |
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| 引用本文： | 欧俊,张慧琴,朱旻,佘立平,松迪,惠宁.半量GnRH拮抗剂方案对IVF-ET控制性超促排卵(COH)的临床效果[J].生殖与避孕,2011,31(9):632-634. |
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| 作者姓名： | 欧俊 张慧琴 朱旻 佘立平 松迪 惠宁 |
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| 作者单位： | 第二军医大学附属长海医院生殖医学中心,上海,200433 |
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| 摘 要： | 目的:探讨半量促性腺激素释放激素拮抗剂(GnRHA)方案对体外授精-胚胎移植(IVF-ET)超促排卵的临床结局。方法:回顾性分析272例行IVF-ET治疗的患者,半量GnRHA方案组(A组)共136个周期和GnRH激动剂(GnRHa)长方案组(B组)136个周期。比较2种控制性超促排卵(COH)方案的临床结局。结果:A组的Gn使用剂量、使用天数、获卵数、胚胎种植率和多胎率均小于B组(P<0.05),而受精率、卵裂率、优质胚胎形成率及临床妊娠率组间无统计学差异(P>0.05)。结论:对正常卵巢储备的患者COH后行IVF-ET结局而言,半量GnRHA方案可以取得与标准GnRHa长方案一样的效果,并可减少Gn的使用天数及剂量,减轻患者的负担。
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| 关 键 词： | GnRH拮抗剂(GnRHA) GnRH激动剂(GnRHa) 体外受精-胚胎移植(IVF-ET) |
Clinical Efficacy of Half-dose GnRH Antagonist on Protocol during Controlled Ovarian Hyperstimulation (COH) for IVF-ET |
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| Jun OU,Hui-qin ZHANG,Ming ZHU,Li-ping SHE,Di SONG,Ning HUI.Clinical Efficacy of Half-dose GnRH Antagonist on Protocol during Controlled Ovarian Hyperstimulation (COH) for IVF-ET[J].Reproduction and Contraception,2011,31(9):632-634. |
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| Authors: | Jun OU Hui-qin ZHANG Ming ZHU Li-ping SHE Di SONG Ning HUI |
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| Institution: | Jun OU,Hui-qin ZHANG,Ming ZHU,Li-ping SHE,Di SONG,Ning HUI(Department of Reproductive Medicine Center,Department of Gynecology and Obstetrics,Changhai Hospital Affiliated to the Second Military Medical University,Shanghai,200433) |
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| Abstract: | Objective: To explore the efficacy of half-dose GnRH-antagonist(GnRNA) on the outcome in patients undergoing controlled ovarian hyperstimulation(COH) for IVF-ET.Methods: A total of 272 patients who underwent IVF-ET were enrolled in this study.They were divieded into group A and group B acording to half-dose GnRHA protocol and GnRH agonist(GnRHa) long protocol,136 cycles per group.The duration of gonadotrophins(Gn) administration,the number of oocytes retrieved,fertilization rates,cleavage rates,the number o... |
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| Keywords: | GnRH antagonist(GnRHA) GnRH agonist(GnRHa) IVF-ET |
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