| 鼻咽癌患者外周血CD4+CD25high Treg 细胞在肿瘤进展中的变化 |
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| 引用本文： | 何金龙,巫翠萍,周小柳,万江花,覃西,李群.鼻咽癌患者外周血CD4+CD25high Treg 细胞在肿瘤进展中的变化[J].临床检验杂志,2011,29(2):94-96. |
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| 作者姓名： | 何金龙 巫翠萍 周小柳 万江花 覃西 李群 |
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| 作者单位： | 海南医学院附属医院检验科，海口571101;海南医学院附属医院检验科，海口571101;海南医学院附属医院耳鼻喉科，海口571101;海南医学院附属医院放射科，海口571101;海南医学院附属医院检验科，海口571101;海南医学院病理教研室，海口570102 |
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| 基金项目： | 海南省自然科学基金（061010）。 |
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| 摘 要： | 目的 观察分析鼻咽癌(nasopharyngeal carcinoma,NPC)患者外周血CD4+CD25high调节性T细胞(regulatory T cells,Treg)在肿瘤进展中的变化与意义.方法 用流式细胞仪检测52例NPC患者、8例鼻咽黏膜慢性炎(nasopharyngitis,NPi)患者、7例头颈部其...
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| 关 键 词： | 调节性T淋巴细胞 鼻咽肿瘤 流式细胞术 肿瘤分期 |
| 收稿时间： | 5/4/2010 12:00:00 AM |
| 修稿时间： | 2010/9/14 0:00:00 |
Variation of CD4+CD25highTreg in peripheral blood of patients with nasopharyngeal carcinoma |
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| HE Jin-longa,WU Cui-pinga,ZHOU Xiao-liub,WAN Jiang-huac,QIN Xia,LI Qun.Variation of CD4+CD25highTreg in peripheral blood of patients with nasopharyngeal carcinoma[J].Chinese Journal of Clinical Laboratory Science,2011,29(2):94-96. |
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| Authors: | HE Jin-longa WU Cui-pinga ZHOU Xiao-liub WAN Jiang-huac QIN Xia LI Qun |
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| Institution: | HE Jin-long1a,WU Cui-ping1a,ZHOU Xiao-liu1b,WAN Jiang-hua1c,QIN Xi1a,LI Qun2(1.a.Department of Clinical Laboratory,b.Department of Otorhinolaryngology,c.Department of Radiology,Affiliated Hospital of Hainan Medical College,Haikou 570102,Hainan,2.Department of Pathology,Hainan Medical College,Haikou 571101,China) |
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| Abstract: | Objective The changes of CD4+CD25high regulatory T cells(Treg) in peripheral blood of the patients with nasopharyngeal carcinoma(NPC) were observed to explore the effect of peripheral Treg on NPC progression.Methods The ratio of CD3+,CD4+,CD8+ T cells and CD4+CD25high Treg in peripheral blood samples were examined with flow cytometry.The blood samples were collected from the patients of 52 NPC,8 nasopharyngitis(NPi),7 other head and neck malignant tumors and 15 healthy individuals.Results The levels of Treg... |
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| Keywords: | regulatory T lymphocyte nasopharyngeal neoplasm flow cytometry neoplasm staging |
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