| 家族性胃癌研究进展 |
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| 引用本文： | 于俊秀,李振方.家族性胃癌研究进展[J].国际肿瘤学杂志,2013,40(1):65-68. |
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| 作者姓名： | 于俊秀 李振方 |
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| 作者单位： | 于俊秀 (252000,山东省聊城市人民医院胃肠外科)； 李振方 (252000,山东省聊城市人民医院胃肠外科)； |
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| 摘 要： |
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Research progress of familial gastric cancer |
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| Abstract: | The etiology of familial gastric cancer (FGC) are E-cadherin (CDH1) mutations, helicobacter pylori infection, etc. The median age of patients with FGC is 50-65 years old. The male-female sex ratio is 2:1. The most of tumors of FGC locate in distal stomach and present diffuse type in histological classification. It is reported that the people who has a family history of gastric cancer especially for those parents has an increased risk of gastric cancer. It is difficult to find FGC in early stage by current technology. The preventive methods include eradication of helicobacter pylori and prophylactic total gastrectomy, etc. |
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| Keywords: | Stomach neoplasms Family Heredity |
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