| 阿莫西林克拉维酸钾(7:1)干混悬剂工艺及稳定性研究 |
| |
| 引用本文： | 吴小玉,常学军,李嘉宇,游窑生.阿莫西林克拉维酸钾(7:1)干混悬剂工艺及稳定性研究[J].中国药师,2006,9(5):394-397. |
| |
| 作者姓名： | 吴小玉 常学军 李嘉宇 游窑生 |
| |
| 作者单位： | 1. 湖北省医药工业研究院有限公司,武汉,430061
2. 武汉同济明治医药有限公司 |
| |
| 摘 要： | 目的:研究阿莫西林克拉维酸钾干混悬剂工艺及其稳定性。方法:采用高效液相色谱法测定阿莫西林和克拉维酸的含量。结果:湿度是影响本制剂质量的关键因素,制备环境湿度控制在33％以内。结论:本制剂在低湿的干燥环境下制备和贮藏是稳定的。
|
| 关 键 词： | 阿莫西林克拉维酸钾 干混悬剂 工艺研究 高效液相色谱法 稳定性 |
| 文章编号： | 1008-049X(2006)05-0394-04 |
| 收稿时间： | 2005-10-14 |
| 修稿时间： | 2005-12-01 |
Study on Preparation and Stability of Amoxicillin and Clavulanate Potassium (7:1 ) for Suspension |
| |
| Wu Xiaoyu,Chang Xuejun,Li Jiayu,You Yaosheng.Study on Preparation and Stability of Amoxicillin and Clavulanate Potassium (7:1 ) for Suspension[J].China Pharmacist,2006,9(5):394-397. |
| |
| Authors: | Wu Xiaoyu Chang Xuejun Li Jiayu You Yaosheng |
| |
| Institution: | 1. Hubei Pharmaceutical Industry Institute Co. Ltd. , Wuhan 430061, P. R. China; 2. Wuhan Tongji Mingzhi Medicine Co. Ltd |
| |
| Abstract: | Objective: To study the preparation and stability of amoxicillin and clavulanate potassium for suspension. Method: HPLC was used to determinate stability. Result: Environmental humidity was the most important factor and should be controlled below 33%. Conclusion: The preparation and storage of amoxicillin and clavulanate potassium for suspension is stability under low humidity. |
| |
| Keywords: | Amoxicillin and clavulanate potassium For suspension Preparing HPLC Stability |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国药师》浏览原始摘要信息 |
| 点击此处可从《中国药师》下载免费的PDF全文 |
