Trout hepatic enzyme activation of aflatoxin B1 in a mutagen assay system and the inhibitory effect of PCBs |
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Authors: | W T Stott R O Sinnhuber |
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Institution: | (1) Department of Food Science and Technology, Oregon State University, 97331 Corvallis, Ore. |
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Abstract: | In summary, it was demonstrated that the trout PMF may be successfully employed in the Ames mutagen assay method by utilization of proper salts solution and a metabolic preincubation period at 25 degrees C. It has also been observed that, unlike the rat, pretreatment of rainbow trout with various PCBs decrease the mutagen assay response to AFB. |
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