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Trout hepatic enzyme activation of aflatoxin B1 in a mutagen assay system and the inhibitory effect of PCBs
Authors:W T Stott  R O Sinnhuber
Institution:(1) Department of Food Science and Technology, Oregon State University, 97331 Corvallis, Ore.
Abstract:In summary, it was demonstrated that the trout PMF may be successfully employed in the Ames mutagen assay method by utilization of proper salts solution and a metabolic preincubation period at 25 degrees C. It has also been observed that, unlike the rat, pretreatment of rainbow trout with various PCBs decrease the mutagen assay response to AFB.
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