|
|||||
|
|
Current concepts of the role of abdominal compartment syndrome in acute pancreatitis – An opportunity or merely an epiphenomenon |
|
| Institution: | 1. Department of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland;2. Department of Anaesthesiology and Intensive Care, University of Tartu, Tartu, Estonia;3. Department of Intensive Care, Fiona Stanley Hospital, Perth, WA, Australia;4. Medical School, The University of Western Australia, Perth, WA, Australia;5. Medical School, The University of Notre Dame, Fremantle, WA, Australia;6. Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia;7. Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia |
| Abstract: | The association of acute pancreatitis (AP) with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) has only recently been recognized. The detrimental effects of raised intra-abdominal pressure in cardiovascular, pulmonary and renal systems have been well established. Although IAH was associated with a higher APACHE II score and multi-organ dysfunction syndrome (MODS) in severe acute pancreatitis, a causal relationship between ACS and MODS in SAP is yet to be established. It is therefore debatable whether IAH is a phenomenon causative of organ failure or an epiphenomenon seen in conjunction with other organ dysfunction. This review systemically examines the pathophysiological basis and clinical relevance of ACS in AP and summarizes all the available evidence in its management. |
| Keywords: | Abdominal compartment syndrome Intra-abdominal hypertension Acute pancreatitis Severe acute pancreatitis Decompressive laparotomy Intra-abdominal pressure |
| 本文献已被 ScienceDirect 等数据库收录！ | |