Peripheral nerve repair: a hot spot analysis on treatment methods from 2010 to 2014 |
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| Authors: | Guang-yao Liu Yan Jin Qiao Zhang Rui Li |
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| Affiliation: | 1.Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China;2.Department of Ophthalmology, the Second Hospital of Jilin University, Changchun, Jilin Province, China;3.Hand & Foot Surgery and Reparative & Reconstruction Surgery Center, the Second Hospital of Jilin University, Changchun, Jilin Province, China |
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| Abstract: | Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research. Advances in basic research in recent years have increased our understanding of the anatomy of peripheral nerves and the importance of the microenvironment. Various new intervention methods have been developed, but with varying effectiveness. In the present study, we selected 911 papers on different repair methods for peripheral nerve injury from the Web of Science and indexed in the Science Citation Index from 2010 to 2014. We quantitatively examine new repair methods and strategies using bibliometrics, and we discuss the present state of knowledge and the problems and prospects of various repair methods, including nerve transfer, neural transplantation, tissue engineering and genetic engineering. Our findings should help in the study and development of repair methods for peripheral nerve injury. |
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| Keywords: | nerve regeneration peripheral nerve injury nerve repair neural transplantation nerve transfer tissue engineering genetic engineering bibliometrics Web of Science neural regeneration |
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