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Performance analysis of four nonlinearity analysis methods using a model with variable complexity and application to uterine EMG signals
Affiliation:1. UMR CNRS 7338, Biomécanique et Bio-ingénierie, Université de Technologie de Compiègne, Compiègne, France;2. School of Science and Engineering, Reykjavik University, Reykjavik, Iceland;3. Laboratoire Traitement du Signal et de L’Image, INSERM, Université de Rennes 1, Campus de Beaulieu, Rennes, France;1. Orthopaedic Research Laboratory, University of Utah Orthopaedic Center, Salt Lake City, UT 84108, USA;2. Bone and Joint Research Laboratory, Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA;3. Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA;1. IRCCS “San Raffaele Pisana”, San Raffaele SPA, via della Pisana 235, 00163 Roma, Italy;2. Department of Electronic, Information and Bioengineering, Politecnico di Milano, p.zza Leonardo Da Vinci 32, 20133 Milano, Italy;1. Department of Electronics and Computer Engineering, Ngee Ann Polytechnic, 599489, Singapore;2. Department of Biomedical Engineering, School of Science and Technology, SIM University, Singapore;3. Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Malaysia;4. Department of Engineering Science, Ngee Ann Polytechnic, Singapore;5. Department of Gynecology, Dr TMA Pai Memorial Rotary Hospital, Karkala, India;6. Department of Ophthalmology, Kasturba Medical College, Manipal 576104, India
Abstract:Several measures have been proposed to detect nonlinear characteristics in time series. Results on time series, multiple surrogates and their z-score are used to statistically test for the presence or absence of non-linearity. The z-score itself has sometimes been used as a measure of nonlinearity. The sensitivity of nonlinear methods to the nonlinearity level and their robustness to noise have rarely been evaluated in the past. While surrogates are important tools to rigorously detect nonlinearity, their usefulness for evaluating the level of nonlinearity is not clear. In this paper we investigate the performance of four methods arising from three families that are widely used in non-linearity detection: statistics (time reversibility), predictability (sample entropy, delay vector variance) and chaos theory (Lyapunov exponents). We used sensitivity to increasing complexity and the mean square error (MSE) of Monte Carlo instances for quantitative comparison of their performances. These methods were applied to a Henon nonlinear synthetic model in which we can vary the complexity degree (CD). This was done first by applying the methods directly to the signal and then using the z-score (surrogates) with and without added noise. The methods were then applied to real uterine EMG signals and used to distinguish between pregnancy and labor contraction bursts. The discrimination performances were compared to linear frequency based methods classically used for the same purpose such as mean power frequency (MPF), peak frequency (PF) and median frequency (MF). The results show noticeable difference between different methods, with a clear superiority of some of the nonlinear methods (time reversibility, Lyapunov exponents) over the linear methods. Applying the methods directly to the signals gave better results than using the z-score, except for sample entropy.
Keywords:Nonlinear time series analysis  Uterine electromyogram  Contraction discrimination  Surrogates
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