A novel device for the clearance and prevention of blockages within biomedical catheters |
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| Affiliation: | 1. Division of Neurosurgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada;2. Department of Surgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada;1. Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology of Chinese Academy of Sciences, Shenzhen, Guangdong, China;2. Beijing Center for Mathematics and Information Interdisciplinary Sciences, Beijing, China;3. Shenzhen Key Laboratory for MRI, Shenzhen, Guangdong, China;1. Key Laboratory for Biomechanics and Mechanobiology of the Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, 37 Xueyuan Road, Haidian District, Beijing, 100191, PR China;2. Tianjin Medical University General Hospital, Tianjin, 300052, PR China;1. Cryogenic Engineering Laboratory, Division of Mechanical Engineering, School of Mechanical, Aerospace and Systems Engineering, Korea Advanced Institute of Science and Technology 373-1, Guseong-dong, Yuseong-gu, Daejeon, 305-701, South Korea;2. Samsung Electronics, Samsung Digital City, Metan-dong, Youngtong-gu, Suwon 443-370, South Korea;3. Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine 120-1 Neungdong-ro, Hwayang-Dong, Gangjin-gu, Seoul, South Korea;4. Korea Aerospace Research Institute, 115 Gwahang-ro, Yuseong-gu, Daejeon, 305-806, Republic of Korea;1. Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK;2. School of Mechanical Engineering, Xi’an Jiaotong University, China |
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| Abstract: | Biomedical catheters are commonly used to move fluids from one part of the body to another, or remove them from the body completely. In some instances, these catheters become occluded due to blood or other debris. Such occlusions may prove fatal or require re-operation with enormous costs and effects on the health-care system and the individual. We developed a model of occlusion in both a ventriculo-peritoneal shut system and en external ventricular drain. Having demonstrated that occlusions can be reliably generated in a manner that resembles the clinical situation we show that vibration can clear the blockages. Vibration in the 50–60 Hz range was able to maintain patency in the catheters or to clear the blockage when the catheter was completely occluded. In high concentrations of blood, 150 s of vibration applied every 30 min was able to maintain the patency of the catheter. Clinically, as the level of blood in the fluid decreases, the time intervals between vibration applications could be increased. We believe that vibration offers a safe, non-invasive method to maintain the patency of biomedical catheters. |
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| Keywords: | Catheter Vibration Hydrocephalus EVD Shunt |
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