Fatigue behaviour of Nitinol peripheral stents: The role of plaque shape studied with computational structural analyses |
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| Institution: | 1. Laboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering ‘Giulio Natta’, Politecnico di Milano, Italy;2. Department of Civil and Environmental Engineering, Politecnico di Milano, Italy;1. Mechanical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Ireland;2. Biomedical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Ireland;1. Fraunhofer Institute for Machine Tools and Forming Technologies, Dresden, Germany;2. Innovation Center Computer Assisted Surgery, Leipzig, Germany;3. Weisseritztal-Kliniken GmbH, Freital, Germany;4. Herzzentrum Leipzig GmbH, University Hospital, Leipzig, Germany;5. Mount Sinai Hospital, Cardiothoracic Surgery, New York, USA;1. Dept of Surgery, University of Nebraska Medical Center, Omaha, NE, United States;2. Dept of Chemical Engineering, University of Maryland, Baltimore County, MD, United States;3. Dept of Mechanical and Materials Engineering, University of Nebraska–Lincoln, Lincoln, NE, United States;1. Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA;2. Department of Genetics, Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, NE, USA;3. Department of Surgery and VA Research Service, VA Nebraska-Western Iowa Health Care System, Omaha, NE, USA;4. Physicians Laboratory Services, Omaha, NE and UNL׳s Forensic Science, Lincoln, NE, USA;5. Department of Mechanical & Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA;1. Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA;2. Department of Surgery and VA Research Service, VA Nebraska-Western Iowa Health Care System, Omaha, NE, USA;3. Department of Mechanical & Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA;4. Physicians Laboratory Services, Omaha, NE, USA;5. Forensic Science with UNL’s Forensic Science Degree Program, Lincoln, NE, USA |
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| Abstract: | Fatigue resistance of Nitinol stents implanted into femoro-popliteal arteries is a critical issue for the particular biomechanical environment of this district. Hip and knee joint movements due to the cyclic daily activity expose the superficial femoral artery (SFA), and therefore the implanted stents, to quite large and cyclic deformations influencing stent fatigue resistance. Objective of this work is to provide a tool based on finite element analysis able to evaluate the biomechanical effect of SFA on stent fatigue resistance. Computer simulations of the treatment of stenotic vessel by angioplasty and stenting and of the subsequent in vivo loading conditions (axial compression and bending) were carried out. Three different stenotic vessel models were defined, by keeping a constant stenosis rate and changing the plaque sharpness and number of stenoses. The fatigue behaviour was analysed comparing the amplitude and mean value distribution of the first principal strain in the whole stent for the different simulated conditions. Results showed that the maximum mean strain is similar in all the models, while the alternating strain is related to both plaque shape and loading conditions. In conclusion, this study confirms the requisite of replicating in vivo loading conditions. It also reveals the importance of taking into account the thickness variation of the vessel in the stenotic zone in the assessment of the stent fatigue resistance. |
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| Keywords: | Finite element analysis Peripheral arteries Shape memory alloy Fatigue fracture Endovascular treatment |
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