Characterization of a CMOS sensing core for ultra-miniature wireless implantable temperature sensors with application to cryomedicine |
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| Affiliation: | 1. School of Engineering, Deakin University, Waurn Ponds, Victoria 3216, Australia;2. Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA;3. Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA;4. Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA;5. Division of Engineering, Mayo Clinic, Rochester, MN 55905, USA;6. Department of Physics, University of Texas at El Paso, El Paso, TX 79968, USA;7. Deakin University, IMPACT Strategic Research Centre, School of Medicine, Waurn Ponds, Victoria 3216, Australia;8. Orygen, National Centre of Excellence in Youth Mental Health and Centre for Youth Mental Health, Department of Psychiatry and Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia |
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| Abstract: | In effort to improve thermal control in minimally invasive cryosurgery, the concept of a miniature, wireless, implantable sensing unit has been developed recently. The sensing unit integrates a wireless power delivery mechanism, wireless communication means, and a sensing core—the subject matter of the current study. The current study presents a CMOS ultra-miniature PTAT temperature sensing core and focuses on design principles, fabrication of a proof-of-concept, and characterization in a cryogenic environment. For this purpose, a 100 μm × 400 μm sensing core prototype has been fabricated using a 130 nm CMOS process. The senor has shown to operate between −180 °C and room temperature, to consume power of less than 1 μW, and to have an uncertainty range of 1.4 °C and non-linearity of 1.1%. Results of this study suggest that the sensing core is ready to be integrated in the sensing unit, where system integration is the subject matter of a parallel effort. |
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| Keywords: | Temperature sensor Miniature Ultra low-power Implant All-CMOS Cryomedicine Cryosurgery |
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