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Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy |
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| Authors: | Frauke Nitzki Ezequiel J. Tolosa Nicole Cuvelier Anke Frommhold Gabriela Salinas-Riester Steven A. Johnsen Martin E. Fernandez-Zapico Heidi Hahn |
| Affiliation: | 1. Department of Human Genetics, University Medical Center, Göttingen, Germany;2. Schulze Center for Novel Therapeutics, Division of Oncology Research, Mayo Clinic, Rochester, MN, USA;3. Microarray and Deep-Sequencing Core Facility, University Medical Center, Göttingen, Germany;4. Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Göttingen, Germany |
| Abstract: | |
| Keywords: | RMS Ptch Gli1 DNA hypomethylation H3K4me3 |