| 脑梗死患者血清细胞因子和C-反应蛋白水平的变化及其意义 |
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| 引用本文： | 魏俊香,王志芬,赵世刚,舒晓伟. 脑梗死患者血清细胞因子和C-反应蛋白水平的变化及其意义[J]. 临床神经病学杂志, 2009, 22(4) |
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| 作者姓名： | 魏俊香 王志芬 赵世刚 舒晓伟 |
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| 作者单位： | 内蒙古妇幼保健医院内科,呼和浩特,010020;内蒙古医学院附属医院神经内科;内蒙古医院神经内科 |
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| 摘 要： | 目的观察脑梗死(CI)患者血清细胞因子——白介素-1β(IL-1β)、IL-6、肿瘤坏死因子-α(TNF-α)及C-反应蛋白(CRP)水平的变化及其意义。方法应用放射免疫法测定合并糖尿病(DM)CI患者(DMCI组,30例)、非DM的CI患者(NDMCI组,30例)、DM患者(DM组,20例)和正常对照组(20人)血清IL-1β、IL-6、TNF-α水平;应用免疫比浊法测定血清CRP水平,根据改良爱丁堡+斯堪的那维亚卒中量表神经功能缺损程度评分对CI患者按病情进行分组。结果DMCI组、NDMCI组及DM组血清IL-1β[(0.60±0.04)ng/ml、(0.33±0.03)ng/ml、(0.30±0.02)ng/ml]、IL-6[(231.07±7.68)pg/ml、(141.34±6.50)pg/ml、(118.92±5.82)pg/ml]、TNF-α[(2.70±0.11)ng/ml、(1.85±0.11)ng/ml、(1.21±0.13)ng/ml]及CRP[(7.44±0.26)ml/L、(4.67±0.21)mg/L、(4.54±0.24)mg/L]水平显著高于正常对照组[(0.20±0.03)n...
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| 关 键 词： | 脑梗死 白细胞介素 肿瘤坏死因子-α C-反应蛋白 |
Chenges and its significance of the levels of serum cytokines and C-reactive protein in patients with cerebral infarction |
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| WEI Jun-xiang,WANG Zhi-fen,ZHAO Shi-gang,et al.. Chenges and its significance of the levels of serum cytokines and C-reactive protein in patients with cerebral infarction[J]. Journal of Clinical Neurology, 2009, 22(4) |
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| Authors: | WEI Jun-xiang WANG Zhi-fen ZHAO Shi-gang et al. |
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| Affiliation: | WEI Jun-xiang,WANG Zhi-fen,ZHAO Shi-gang,et al.Department of Medicine,Inner Mongolia Healthcare Hospital of Women , Children,Huhhot 010020,China |
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