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加味增液承气汤治疗阿片类镇痛药所致肠燥津亏型便秘的疗效观察
引用本文:李剑英,方子欣,宋琳,闾艳,陈孟溪.加味增液承气汤治疗阿片类镇痛药所致肠燥津亏型便秘的疗效观察[J].湖南中医药大学学报,2013(9):76-78.
作者姓名:李剑英  方子欣  宋琳  闾艳  陈孟溪
作者单位:[1]湖南省中医药研究院附属医院,湖南长沙410006 [2]湖南中医药大学,湖南长沙410208
摘    要:目的观察加味增液承气汤治疗阿片类镇痛药所致肠燥津亏型便秘的临床疗效。方法选择90例因服用阿片类镇痛药所致便秘的肠燥津亏证癌痛患者,随机分为中药组(加味增液承气汤组)、西药组(乳果糖组)和中西组(加味增液承气汤+乳果糖组),观察2周并随访,评价3组患者的临床综合疗效,包括便秘症状、中医证候改善情况。结果便秘改善情况及中医证候改善情况均为中药组、中西组优于西药组(P<0.05),中西组优于中药组(P<0.05)。结论加味增液承气汤口服能显著改善癌痛患者服用阿片类镇痛药所致肠燥津亏型便秘的便秘程度及伴随症状,联用乳果糖则疗效更佳。

关 键 词:便秘  肠燥津亏  加味增液承气汤  乳果糖  阿片类药

Clinical curative effects of Extra-large Chengqi Decoction in treating bowel dryness and fluid deficiency type constipation caused by opium analgesics
LI Jian-ying,FANG Zi-xin,SONG lin,LV Yan,CHEN Meng-xi.Clinical curative effects of Extra-large Chengqi Decoction in treating bowel dryness and fluid deficiency type constipation caused by opium analgesics[J].Journal of Traditional Chinese Medicine University of Hunan,2013(9):76-78.
Authors:LI Jian-ying  FANG Zi-xin  SONG lin  LV Yan  CHEN Meng-xi
Institution:1. Affiliated Hospital of Hunan Academy of CM, Changsha, Hunan 410007, China; 2. Hunan University of CM, Changsha, Hunan 410208, China)
Abstract:Objective To observe the clinical curative effects of Extra-large Chengqi Decoction in treating bowel dryness and fluid deficiency type constipation caused by opium analgesics. Meth- ods 90 cancer patients with bowel dryness and fluid deficiency type constipation caused by opium analgesics were randomly divided into 3 groups: TCM Group (Extra-large Chengqi Decoction Group), Western Medicine Group(lactulose Group) and Integrated Chinese and Western Medicine Group (Ex- tra-large Chengqi Decoction plus lactulose Group). 3 groups were treated and observed for 2 weeks. Clinical efficacy was evaluated including improvement of constipation symptom and TCM syndromes. Results Improvement of constipation symptom and TCM syndromes in TCM Group and Integrated Chinese and Western Medicine Group was better than Western Medicine Group (P〈0.05); the effects in Integrated Chinese and Western Medicine Group were better than TCM Group (P〈0.05). Conclu- sion Extra-large Chengqi Decoction can significantly help cancer patients to improve bowel drynessand fluid deficiency type constipation and accompanying symptoms caused by opium analgesics. The further better effects can be added by combining with lactulose oral solution.
Keywords:constipation  bowel dryness and fluid deficiency  Extra-large Chengqi Decoc-tion  lactulose  opioids
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