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Dexamethasone decreases the transmesothelial electrical resistance of the parietal and visceral pleura |
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| Authors: | Sotirios Zarogiannis Triantafyllia Deligiorgi Ioannis Stefanidis Vassilios Liakopoulos Konstantinos Gourgoulianis Paschalis Adam Molyvdas Chrissi Hatzoglou |
| Affiliation: | (1) Department of Physiology, University of Thessaly Medical School, Mezourlo Hill, 41110 Larissa, Greece;(2) Department of Nephrology, University of Thessaly Medical School, Mezourlo Hill, 41110 Larissa, Greece;(3) Department of Respiratory Medicine, University of Thessaly Medical School, Mezourlo Hill, 41110 Larissa, Greece |
| Abstract: | The effect of dexamethasone on the transmesothelial electrical resistance (R TM) of sheep pleura was investigated by Ussing chamber experiments. Our results show that dexamethasone decreases the R TM of sheep pleurae, in part by stimulation of glucocorticoid receptors. This finding may be of importance in regard to the faster resolution of corticosteroid-treated pleural effusions. |
| Keywords: | Corticosteroids Pleural effusion Ussing system |
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