Short physical performance battery discriminates clinical outcomes in hospitalized patients aged 75 years and over |
| |
| Affiliation: | 1. Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan;2. Frankel Cardiovascular Center, Michigan Medicine, Ann Arbor, Michigan;3. Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan;4. Department of Human Genetics, University of Michigan, Ann Arbor, Michigan;5. Ann Arbor Veterans Affairs Health System, Ann Arbor, Michigan;1. Department of Medicine DIMED, Geriatrics Division, University of Padova, Italy;2. Physiotherapy Department, South London and Maudsley NHS Foundation Trust, Denmark Hill, London SE5 8AZ, United Kingdom;3. Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience King''s College London, De Crespigny Park, London SE5 8AF, United Kingdom;4. Department of Neurosciences, University of Padova, Padova, Italy;5. National Health Care System, Padua Local Unit ULSS 17, Italy;6. Institute of Clinical Research and Education in Medicine (IREM), Padova, Italy;7. Department of Medicine DIMED, Clinica Medica I, University of Padova, Italy;8. National Research Council, Neuroscience Institute, Padova, Italy;9. Department of Cardiac, Thoracic and Vascular Sciences - Biostatistics, Epidemiology and Public Health Unit, University of Padova, Padova, Italy;1. Department of Kinesiology and Nutrition, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, United States;2. Program in Exercise Science, Department of Physical Therapy, Marquette University, Milwaukee, WI, United States;3. Center for Neuropsychology and Neuroscience Research, Kessler Foundation, West Orange, NJ, United States;4. Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ, United States |
| |
| Abstract: | AimLow physical function is associated with poor outcomes in hospitalized patients; however, little is known about vulnerable populations such as those aged ≥ 75 years. We examined whether the Short Physical Performance Battery (SPPB) was associated with clinical outcomes in hospitalized patients aged ≥ 75 years.MethodsIn total, 147 patients aged ≥ 75 years (mean age, 86.5 ± 4.7 years; 89 males) completed the SPPB and Mini-Mental State Examination (MMSE) before hospital discharge. Patients were divided into three groups by SPPB score: 0 (unable to perform SPPB), 1–6 (low performance), and 7–12 (high performance). The first occurrence of all-cause unplanned readmission or all-cause mortality within 1 year after discharge was set as the endpoint.ResultsThe median SPPB score of the study population was 2; 41 % were unable to perform SPPB, 33 % had low performance, and 26 % had high performance. High SPPB was associated with younger age, higher body weight, and higher MMSE score. During the follow-up period, 35 (23.8 %) patients were readmitted to hospital and 19 (12.9 %) died. Even after adjusting for covariates, SPPB score was a significant and independent predictor of poor outcomes (hazard ratio for 1 point increase in SPPB, 0.88; P = .002). The subgroup analysis showed SPPB was inversely associated with the occurrence of poor outcomes in patients with cognitive impairment.ConclusionsSPPB is inversely associated with risks for readmission and mortality in hospitalized patients aged ≥ 75 years, especially those with cognitive impairment. The present results indicate the SPPB is useful for accurate prognosis in hospital settings. |
| |
| Keywords: | Cognitive dysfunction Frail older adults Hospitalization Mortality Physical functional performance |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
