The Mexican Cognitive Aging Ancillary Study (Mex-Cog): Study Design and Methods |
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| Institution: | 1. Department of Population Studies, El Colegio de la Frontera Norte, Tijuana, Baja California, Mexico;2. Independent Consultant;3. Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA;4. Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico;5. Instituto Nacional de Neurologia y Neurocirugia, Mexico City, Mexico;6. Instituto Nacional de Geriatría, Mexico City, Mexico;7. Department of Psychological Medicine, University of Auckland, New Zealand;1. Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, United States;2. Department of Public Health, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, United States;1. School of Public Health, Medical College of Soochow University, Suzhou 215123, China;2. The 3rd People’s Hospital of Xiangcheng District, Suzhou 215134, China;1. Institute of Management and Department EMbeDS, Management and Health Laboratory, Scuola Superiore Sant’Anna, Pisa, Italy;2. Social and Political Sciences Department, Università Bocconi, Milan, Italy;3. CERGAS-SDA, Università Bocconi, Milan, Italy;4. Geriatric Institute “Camillo Golgi”, ASP Golgi Redaelli, Abbiategrasso, Milan, Italy;5. Golgi Cenci Foundation, Abbiategrasso, Milan, Italy;1. Postgraduation Program in Physical Education, Federal University of Santa Catarina, Campus Universitário Reitor João David Ferreira Lima, Prédio administrativo - Centro de Desportos, sala 200 – 2º andar, Trindade, Florianópolis, Santa Catarina, 88040-900, Brazil;2. Postgraduation Program in Collective Health, Federal University of Santa Catarina, Campus Universitário Reitor João David Ferreira Lima, Prédio administrativo - Centro de Desportos, sala 200 – 2º andar, Trindade, Florianópolis, Santa Catarina, 88040-900, Brazil;1. Department of Orthopedics and Traumatology, Päijät-Häme Central Hospital, Lahti, Finland;2. Fimlab Laboratories, Lahti, Finland;3. Department of Public Health, Helsinki University, Helsinki, Finland;4. Department of Information Management, Päijät-Häme Social and Health Care Group, Lahti, Finland;5. Outpatient Department of Surgery, North Kymi Hospital, Kouvola and Kymenlaakso Central Hospital, Carea, Kotka, Finland;6. National Institute for Health and Welfare, Helsinki, Finland;7. Terveystalo, Lahti, Finland;8. North Kymi Hospital, Kouvola, Finland |
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| Abstract: | ObjectiveDescribe the protocol sample and instruments of the Cognitive Aging Ancillary Study in Mexico (Mex-Cog). The study performs an in-depth cognitive assessment in a subsample of older adults of the ongoing Mexican Health and Aging Study (MHAS). The Mex-Cog is part of the Harmonized Cognitive Assessment Protocol (HCAP) design to facilitate cross-national comparisons of the prevalence and trends of dementia in aging populations around the world, funded by the National Institute on Aging (NIA).MethodsThe study protocol consists of a cognitive assessment instrument for the target subject and an informant questionnaire. All cognitive measures were selected and adapted by a team of experts from different ongoing studies following criteria to warrant reliable and comparable cognitive instruments. The informant questionnaire is from the 10/66 Dementia Study in Mexico.ResultsA total of 2,265 subjects aged 55-104 years participated, representing a 70% response rate. Validity analyses showed the adequacy of the content validity, proper quality-control procedures that sustained data integrity, high reliability, and internal structure.ConclusionsThe Mex-Cog study provides in-depth cognitive data that enhances the study of cognitive aging in two ways. First, linking to MHAS longitudinal data on cognition, health, genetics, biomarkers, economic resources, health care, family arrangements, and psychosocial factors expands the scope of information on cognitive impairment and dementia among Mexican adults. Second, harmonization with other similar studies around the globe promotes cross-national studies on cognition with comparable data. Mex-Cog data is publicly available at no cost to researchers. |
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| Keywords: | Cognitive aging Epidemiologic studies Population-based studies Mexico MHAS |
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