Combined effects of frailty status and cognitive impairment on health-related quality of life among community dwelling older adults |
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| Affiliation: | 1. Department of Health Care Management, College of Management, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan;2. Division of Endocrinology and Metabolism, Departments of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Tao-Yuan City, Taiwan;3. Division of Preventive Medicine and Health Service Research, Institute of Population Health Sciences, National Health Research Institutes, #35, Keyan Road, A3223, Zhunan Town, Maoli 350, Taiwan;4. Sydney School of Public Health, University of Sydney, NSW 2006, Australia;1. School of Public Health, University of Haifa, Haifa, Israel;2. Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel;1. School of Physiotherapy, Faculty of Health, Dalhousie University, Halifax, Canada;2. Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, Canada;3. Department of Surgery, Max Rady College of Medicine, University of Manitoba, Canada;4. Health, Leisure & Human Performance Research Institute, Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Canada;5. Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Winnipeg, Canada;6. College of Nursing, Max Rady College of Medicine, Faculty of Heath Sciences, University of Manitoba Winnipeg, Canada;7. Cardiac Sciences Program, St. Boniface Hospital, Winnipeg, Canada;8. Seven Oaks Hospital Research Centre, Winnipeg, Canada;1. Research Unit of Physical Activity and Sport at Faculty of Sport Sciences and Physical Education (CIDAF, UID/PDT/04213/2016) – University of Coimbra, Portugal;2. Laboratory of Sport and Exercise Psychology of Faculty of Sport Sciences and Physical Education of University of Coimbra, Portugal;3. School of Sport, Exercise and Health Sciences, Loughborough University, United Kingdom;4. CIAMS, University Paris-Sud, Université, Paris-Saclay, 91405, Orsay Cedex, France;5. CIAMS, Université d''Orléans, 45067, Orléans, France;6. Research Team ECRIN, INRA, UMR 1019, Clermont-Ferrand, France;7. Medical Psychology Unit, School of Medicine, Clinical Neuroscience and Mental Health, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal |
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| Abstract: | ObjectivesThe aim of the present study was to investigate the combined association of frailty/pre-frailty and cognitive impairment with health related quality of life (HRQOL) among community dwelling older adults.MethodsData came from a cross-sectional study of community-dwelling older adults aged 65 years or older, who participated in the 2013 National Health Interview Survey in Taiwan. Frailty was determined based on the Fatigue, Resistance, Ambulation, Illness, and Loss of weight (FRAIL) scale proposed by the International Association of Nutrition and Aging. The Mini-Mental State Examination was used to assess cognitive function. HRQOL was measured using the European Quality of Life-5 Dimensions questionnaire (EQ-5D) that assesses three levels of functioning for the dimensions of mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Poisson regression models were performed to estimate prevalence ratios (PR) and 95 % Confidence Intervals (95 % CI) for health problems in all EQ-5D domains.ResultsIn this study, 11.0 % of participants aged 65 years and older had co-occurring frailty/pre-frailty and cognitive impairment. After adjustment for other factors, compared with participants who were physically robust with normal cognition, participants with co-occurring frailty/pre-frailty and cognitive impairment had PRs of 10.38 (95 % CI 7.56–14.26), 9.66 (95 % CI 6.03–15.48), 9.37 (95 % CI 6.92–12.68), 3.04 (95 % CI 2.53–3.64), and 5.63 (95 % CI 3.83–8.28) for reporting problems with mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, respectively.ConclusionsThere is a high prevalence of co-occurrence of frailty/pre-frailty and cognitive impairment in older adults, and this co-occurrence was strongly associated with self-reported health problems across all EQ-5D domains. |
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| Keywords: | Frailty Cognitive impairment Health related quality of life Taiwan |
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