畸变产物耳声发射对侧抑制效应的临床应用价值

目的：为观察畸变产物耳声发射（ＤＰＯＡＥ）对侧抑制效应的临床应用价值。方法：研究以白噪声为对侧声刺激，对１７例正常人（３４耳），１３例蜗性聋（１３耳），９例蜗后聋（９耳）进行了ＤＰＯＡＥ及其对偶抑制效应测试。结果：蜗性聋耳的ＤＰＯＡＥ幅值较正常耳显著下降（Ｐ〈０．０１），对偶抑制效应减弱，但与正常人差异无统计学意义（Ｐ〉０．０５），蜗后聋耳ＤＰＯＡＥ幅值高于正常耳（Ｐ〉０．０５），对侧抑制效应显著

Clinical value of distortion product otoacoustic emission (DPOAE) and their contralateral suppression effects

The present paper aimed at examining the role of DPOAE and their contralatefal suppressive effects in evaluation medial olivocochlear system (MOCS) function status in human. Method:Seventeensubjects (34 ears) with normal hearing, 13 ears with cochlear hearing loss and 9 ears with retrocochlear hearingloss were studied on their DPOAE and contralateral suppression. Result:The results revealed that DPOAE amplitude significantly reduced in ears with cochlear hearing loss,contralateral suppression was smaller than normalears but there was no significant difference between two groups. By contrast,DPOAE amplitude was much higherin ears with retrocochlear hearing loss than that in the other two groups. Contralateral suppression was significantly reduced or disappeared,and contralateral acoustic stimulus (CAS) even increased DPOAE amplitude in earswith retrocochlear hearing loss. Conclusion: DPOAE and suppression induced by CAS can be used as an index ofmedial olivocochlear system (MOCS) function in patients with sensori-neuaral hearing loss,and can differentiatecochlear hearing loss from retrocochlear hearing loss. The tests of DPOAE and contralateral suppression mayhave much more advantages in clinical application over any other audiological test.