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| 引用本文： | 赖永榕. ��Ѫ��ϸ����ֲ����������Ѫ��ƶѪ�����е�Ӧ��[J]. 中国实用内科杂志, 2012, 32(5): 344-346 |
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| 作者姓名： | 赖永榕 |
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| 作者单位： | 广西医科大学第一附属医院血液内科 |
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| 摘 要： | 造血干细胞移植(HSCT)是目前惟一能治愈先天性溶血性贫血(如重型地中海贫血和鐮状细胞贫血)的治疗方法。HLA相合同胞供者移植治疗儿童患者的总生存(OS)率超过90%,无事件生存(EFS)率超过80%。无关供者移植使更多无HLA相合同胞供者的患者获得移植机会。
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| 关 键 词： | 造血干细胞移植 地中海贫血 镰状细胞贫血 |
The application of hematopoietic stem cell transplantation in treatment of congenital hemolytic anemia |
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| LAI Yong-rong. The application of hematopoietic stem cell transplantation in treatment of congenital hemolytic anemia[J]. Chinese Journal of Practical Internal Medicine, 2012, 32(5): 344-346 |
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| Authors: | LAI Yong-rong |
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| Affiliation: | LAI Yong-rong.Department of Hematology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China |
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| Abstract: | Hematopoietic stem cell transplantation(HSCT) remains the only treatment method that can cure congenital hemolytic anemia such as severe thalassemia and sickle cell anemia(SCA) at present.The overall survival(OS) is over 90% in children treated with HLA-identical sibling donor transplantation,while event-free survival(EFS) is over 80%.The event-free donor transplantation enables more patients without HLA-identical sibling donors to obtain transplantation chances. |
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| Keywords: | hematopoietic stem cell transplantation thalassemia sickle cell anemia |
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