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二甲双胍致不良反应的文献分析
引用本文:苏娜,徐珽,唐尧. 二甲双胍致不良反应的文献分析[J]. 华西医学, 2011, 0(11): 1608-1610
作者姓名:苏娜  徐珽  唐尧
作者单位:四川大学华西医院药剂科
摘    要:目的 探讨二甲双胍致不良反应的一般规律和特点.方法 检索1994年- 2011年中国期刊全文数据库中二甲双胍所致不良反应个案报道的文献,得到符合条件的文献29篇共33例,进行统计分析.结果 33例不良反应主要表现为内分泌系统(48.5%),皮肤及附件(18.2%),变态反应(15.2%),消化系统(9.1%),神经系统...

关 键 词:二甲双胍  不良反应  文献分析

A Literature Analysis of Adverse Drug Reactions Induced by Metformin
SU Na,XU Ting,TANG Yao. A Literature Analysis of Adverse Drug Reactions Induced by Metformin[J]. West China Medical Journal, 2011, 0(11): 1608-1610
Authors:SU Na  XU Ting  TANG Yao
Abstract:Objective To investigate the characteristics and the general pattern of the adverse drug reactions(ADR) induced by metformin.Methods The ADR induced by metformin reported in domestic medical journals during 1994-2008 were retrieved by means of CNKI.A total of 29 related literatures involving 33 cases,and a related database was established for statistical analysis.Results The main clinical manifestation represented as endocrine system(48.5%),lesion of skin and its appendants(18.2%),allergic reactions(15.2%),digestive system(9.1%),nervous system(6.1%) and so on.Conclusion It is necessary to pay attention to ADR induced by metformin and strengthen observation during medication in order to reduce serious ADR.
Keywords:Metformin  Adverse drug reactions  Literature analysis
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