腰池置管脑脊液外引流治疗颅内感染临床分析

目的 观察持续腰池置管脑脊液外引流治疗颅内感染的疗效.方法 2008年9月-2009年11月,将20例颅脑外伤后颅内感染患者分为脑脊液外引流组和抗生素组各10例,外引流组进行持续腰池置管脑脊液外引流,定期取引流脑脊液进行常规和生化检查;抗生素组采用静脉抗生素治疗.对两组颅内感染情况进行对比分析.结果 外引流组经持续腰...

A Clinical analysis of Lumbar Drainage of Cerebrospinal Fluid in Treating Intracranial Infection

Objective To observe the efficacy of continuous lumbar drainage of cerebrospinal fluid via a lumbar catheter in treating intracranial infection.Methods From September 2008 to November 2009,20 patients with intracranial infection after head trauma were enrolled in this study.Ten of them,classified as the external drainage group,sustained continuous external lumbar drainage of cerebrospinal fluid.The cerebrospinal fluid was obtained regularly for routine and biochemical examination.The other 10 patients were categorized as the antibiotics group.They only accepted intravenous antibiotic therapy.Results For the patients in the external drainage goup,after continuous external lumbar drainage of cerebrospinal fluid,their clinical symptoms of intracranial infection were significantly alleviated and the number of nucleated cells and protein content in the cerebrospinal fluid decreased significantly,while the glucose and chloride concentrations increased significantly（P〈0.05）.After 10 days of treatment,the patients in the external drainage group were superior to those in the antibiotics group in improvement of the body temperature,the number of nucleated cells and protein content,glucose and chloride concentrations in the cerebrospinal fluid（P〈0.05）.Conclusion Continuous lumbar drainage of cerebrospinal fluid is simple and safe.It provides an easy way of monitoring the intracranial infection and can be a reliable treatment.