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动态三维超声造影评估原发性肝细胞癌射频消融后的近期疗效
引用本文:张丹,周华玲,唐潮浪. 动态三维超声造影评估原发性肝细胞癌射频消融后的近期疗效[J]. 世界华人消化杂志, 2019, 27(8): 530-534
作者姓名:张丹  周华玲  唐潮浪
作者单位:杭州市下城区中医院B超室 浙江省杭州市 310004;嘉兴市第二医院超声诊断科 浙江省嘉兴市 314000;中国人民武装警察部队浙江省总队医院卫勤处 浙江省嘉兴市 314000
摘    要:背景射频消融(radiofrequency ablation, RFA)在非手术治疗肝细胞癌(hepatocellular carcinoma, HCC)方面发挥着重要作用,而准确评估术后HCC残留状态对于临床制定下一步治疗方案有着重要指导意义.临床上常常采用各种影像学方法评估RFA疗效.超声因其具有无创、便捷、可重复等优点,在RFA疗效评估方面日益受到临床重视.其中动态三维超声造影(dynamic three-dimensionalcontrast-enhancedultrasound,3DCEUS)能动态显示肿瘤组织在三维立体空间下的血流灌注状态,有望为RFA疗效评估提供一种全新的影像学方法.目的运用3DCEUS评估原发性HCCRFA后的近期疗效,并探讨其临床价值.方法回顾性分析2016-03/2018-11期间,在嘉兴市第二医院接受超声引导下RFA的93例原发性HCC患者,共117个肿瘤.术后1 mo均接受3DCEUS检查,同期行增强磁共振成像(enhanced magnetic resonance imaging,CEMRI)检查.以CEMRI作为疗效评估"金标准",分析3DCEUS在评估RFA疗效中的效能.结果 CEMRI判定82.05%(96/117)的肿瘤完全消融,17.95%(21/117)的肿瘤消融不全;3DCEUS判定82.91%(97/117)的肿瘤完全消融,17.09%(20/117)的肿瘤消融不全.3DCEUS评估RFA后肿瘤残留的敏感度为90.48%(19/21)、特异度为98.96%(95/96)、准确率为97.44%(114/117)分别与CEMRI比较,差异均无统计学意义(P>0.05).结论 3DCEUS能准确评估原发性HCCRFA后的近期疗效,具有较高临床应用价值.

关 键 词:动态三维超声造影  射频消融  原发  肝细胞癌  疗效

Evaluation of short-term efficacy of radiofrequency ablation for hepatocellular carcinoma by dynamic three-dimensional contrast-enhanced ultrasound
Dan Zhang,Hua-Ling Zhou,Chao-Lang Tang. Evaluation of short-term efficacy of radiofrequency ablation for hepatocellular carcinoma by dynamic three-dimensional contrast-enhanced ultrasound[J]. World Chinese Journal of Digestology, 2019, 27(8): 530-534
Authors:Dan Zhang  Hua-Ling Zhou  Chao-Lang Tang
Affiliation:(Department Ultrasound,Hangzhou Xiacheng District Hospital,Hangzhou 310004,Zhejiang Province,China;Department of Ultrasound Diagnosis,Jiaxing Second Hospital,Jiaxing 314000,Zhejiang Province,China;Department of Health and Welfare,Zhejiang Provincial Corps Hospital,Chinese People’s Armed Police Force,Jiaxing 314000,Zhejiang Province,China)
Abstract:Dan Zhang;Hua-Ling Zhou;Chao-Lang Tang(Department Ultrasound,Hangzhou Xiacheng District Hospital,Hangzhou 310004,Zhejiang Province,China;Department of Ultrasound Diagnosis,Jiaxing Second Hospital,Jiaxing 314000,Zhejiang Province,China;Department of Health and Welfare,Zhejiang Provincial Corps Hospital,Chinese People’s Armed Police Force,Jiaxing 314000,Zhejiang Province,China)
Keywords:Dynamic three-dimensional contrast-enhanced ultrasound  Radiofrequency ablation  Hepatocellular carcinoma  Therapeutic effect
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