| 超声造影定量评估TACE术后原发性肝细胞癌的血流灌注变化 |
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| 引用本文： | 张心荣,欧阳骏,黄敬垣.超声造影定量评估TACE术后原发性肝细胞癌的血流灌注变化[J].世界华人消化杂志,2019,27(4):276-281. |
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| 作者姓名： | 张心荣 欧阳骏 黄敬垣 |
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| 作者单位： | 浙江省德清县人民医院B超室 浙江省湖州市 313200;树兰(杭州)医院超声科 浙江省杭州市 310022 |
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| 摘 要： | 目的探讨超声造影(contrast-enhanced ultrasound, CEUS)定量评估经导管肝动脉化疗栓塞术(transcatheter arterychemo-embolization, TACE)后原发性肝细胞癌(Hepatocellular Carcinoma, HCC)残留肿瘤的血流灌注状态及其应用价值.方法选取浙江省德清县人民医院收治并接受TACE治疗的45例HCC患者作为研究对象,共57个肿瘤,分别于治疗前1 d、治疗后1 mo行CEUS,比较TACE前后残留肿瘤的血流灌注参数.结果 CEUS判定HCC肿瘤残留的灵敏度=95.45%,准确度=94.74%,特异度=92.31%;术后HCC残留肿瘤的增强强度(56.87%±4.15%)较治疗前(75.09%±6.42%)明显下降,差异有统计学意义(P<0.05);术后HCC残留肿瘤的达峰时间(25.26 s±3.83 s)较治疗前(21.02s±3.70s)明显延长,差异有统计学意义(P <0.05);术后HCC残留肿瘤的曲线下面积(581.29±86.43)较治疗前(1017.83±111.76)明显减少,差异有统计学意义(P <0.05).结论 CEUS能直观反映HCC经TACE治疗后肿瘤残留状态,并能定量评估残留肿瘤的血流灌注变化,可为临床进一步治疗提供血流动力学信息.
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| 关 键 词： | 超声造影 原发性肝细胞癌 经导管肝动脉化疗栓塞术 血流灌注 |
Quantitative evaluation of blood perfusion in hepatocellular carcinoma after transcatheter arterial chemoembolization by contrast-enhanced ultrasound |
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| Xin-Rong Zhang,Jun Ouyang,Jing-Yuan Huang.Quantitative evaluation of blood perfusion in hepatocellular carcinoma after transcatheter arterial chemoembolization by contrast-enhanced ultrasound[J].World Chinese Journal of Digestology,2019,27(4):276-281. |
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| Authors: | Xin-Rong Zhang Jun Ouyang Jing-Yuan Huang |
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| Institution: | (Department of Ultrasonography,Deqing People’s Hospital,Huzhou 313200,Zhejiang Province,China;Department of Ultrasonography,Shulan (Hangzhou) Hospital,Hangzhou 310022,Zhejiang Province,China) |
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| Abstract: | Xin-Rong Zhang;Jun Ouyang;Jing-Yuan Huang(Department of Ultrasonography,Deqing People’s Hospital,Huzhou 313200,Zhejiang Province,China;Department of Ultrasonography,Shulan (Hangzhou) Hospital,Hangzhou 310022,Zhejiang Province,China) |
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| Keywords: | Contrast-enhanced ultrasound Hepatocellular carcinoma Transcatheter arterial chemoembolization Blood perfusion |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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