甲状腺功能亢进症与性腺功能的关系探讨 |
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引用本文: | 王琼,王莉,付建芳,石敏,翟文松,姬秋和,李晓苗.甲状腺功能亢进症与性腺功能的关系探讨[J].陕西医学杂志,2013,42(6):721-723. |
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作者姓名: | 王琼 王莉 付建芳 石敏 翟文松 姬秋和 李晓苗 |
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作者单位: | 王琼 (第四军医大学西京医院内分泌代谢科,西安,710032); 王莉 (陕西省宝鸡市中心医院肾病糖尿病科); 付建芳 (第四军医大学西京医院内分泌代谢科,西安,710032);石敏 (第四军医大学西京医院内分泌代谢科,西安,710032); 翟文松 (第四军医大学西京医院内分泌代谢科,西安,710032); 姬秋和 (第四军医大学西京医院内分泌代谢科,西安,710032); 李晓苗 (第四军医大学西京医院内分泌代谢科,西安,710032); |
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摘 要: | 目的:探讨甲状腺功能亢进症(甲亢)患者病情的严重程度及病程长短与性腺功能之间的关系。方法:对63例甲亢患者进行实验室检查,按病程长短及甲亢严重程度分组,分别测定血清中甲状腺激素、甲状腺自身抗体、促卵泡成熟激素(FSH)、促黄体生成激素(LH)、雌二醇(E2)、孕酮(P)、睾酮(T)和垂体泌乳素(PRL),判断甲状腺功能与性腺功能状态。结果:除男性甲亢患者P外,重度甲亢组与中度、轻度甲亢组比较,FSH、LH、E2、T、PRL均有显著性差异(P<0.05),而病程较长组与病程较短组比较,FSH、LH、E2、T、PRL亦有显著性差异(P<0.05)。结论:甲亢程度越重,病程越长,对性腺功能的抑制程度越大。
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关 键 词: | 甲状腺功能亢进症 性腺功能减退症 因果律 |
The functional change of gonad in patients with hyperthyroidism |
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Abstract: | Objective:To explore the illness severity and duration in patients with hyperthyroidism and relationships between gonad function,providing rationale for clinical treatment.Methods:Serum thyroxin,thyroid autoantibody,follicle-stimulating hormone(FSH),leuteinizing hormone(LH),estradoil(E2),progesterone(P),testosterone(T),prolactin(PRL) was detected and Grouped by course length and severity of hyperthyroidism.Results: Addition to the progesterone in male patients with hyperthyroidism,Severe hyperthyroidism group and moderate,mild hyperthyroidism comparison,FSH,LH,E2,T,PRL has significant differences(P<0.05),and comparison of course longer and shorter course groups,FSH,LH,E2,T,PRL also showed a marked difference(P<0.05).Conclusion: Hyperthyroidism more heavy,long course,the greater the degree of inhibition of gonadal function. |
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Keywords: | Hyperthyroidism Hypogonadism Causality |
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