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内皮祖细胞在肺动脉高压的作用
引用本文:万钧,王辰,王军. 内皮祖细胞在肺动脉高压的作用[J]. 国际呼吸杂志, 2009, 29(22): 1393-1396. DOI: 10.3760/cma.j.issn.1673-436X.2009.022.012
作者姓名:万钧  王辰  王军
作者单位:首都医科大学附属北京朝阳医院呼吸与危重症医学科首都医科大学呼吸病学系北京呼吸疾病研究所,100020;首都医科大学基础医学院生理学教研室,北京,100069
摘    要:内皮祖细胞是成熟血管内皮细胞的前体细胞,属于干细胞群体,其在血管再生与修复方面的应用越来越受到关注.肺动脉高压作为一种致死性很高的肺血管疾病,其发病与血管内皮损伤密切相关.目前的研究证实,内皮祖细胞在肺动脉高压血管内皮修复中具有重要作用,内皮祖细胞移植有可能成为临床治疗肺动脉高压的一种有效手段.

关 键 词:内皮祖细胞  肺动脉高压

Role of endothelial progenitor cells in pulmonary hypertension
WAN Jun,WANG Chen,WANG Jun. Role of endothelial progenitor cells in pulmonary hypertension[J]. International Journal of Respiration, 2009, 29(22): 1393-1396. DOI: 10.3760/cma.j.issn.1673-436X.2009.022.012
Authors:WAN Jun  WANG Chen  WANG Jun
Abstract:Endothelial progenitor cells are precursors of mature vascular endothelial cells,which belong to stem cell populations.More and more researchers pay close attention to the important role of endothelial progenitor cells in vascular regeneration and repair.Pulmonary hypertension is a fatal pulmonary vascular disease.The pathogenesis of pulmonary hypertension relates closely with blood vessel endothelium injury.Present studies have proved that endothelial progenitor cells play important roles in blood vessel endothelium repair of pulmonary hypertension,and transplantation of endothelial progenitor cells could be applied as an effective method for pulmonary hypertension.
Keywords:Endothelial progenitor cells  Pulmonary hypertension
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