| 磷酸化VEGFR在慢性间歇性缺氧兔海马区的蛋白质水平及mRNA水平研究 |
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| 引用本文： | 邹斌,杨宇,罗荧荃.磷酸化VEGFR在慢性间歇性缺氧兔海马区的蛋白质水平及mRNA水平研究[J].实用预防医学,2010,17(8):1513-1515. |
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| 作者姓名： | 邹斌 杨宇 罗荧荃 |
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| 作者单位： | 1. 湖南省长沙市第一医院心内科,湖南,长沙,410005
2. 中南大学湘雅二医院老年科 |
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| 摘 要： |
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| 关 键 词： | 慢性间歇性缺氧 血管表皮生长因子 磷酸化 海马 |
Expression of P-VEGFR mRNA and Proteinic Level in Hippocampus of Rabbit with Chronic Intermittent Hypoxia |
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| ZOU Bin,YANG Yu,LUO Ying-quan.Expression of P-VEGFR mRNA and Proteinic Level in Hippocampus of Rabbit with Chronic Intermittent Hypoxia[J].Practical Preventive Medicine,2010,17(8):1513-1515. |
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| Authors: | ZOU Bin YANG Yu LUO Ying-quan |
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| Institution: | ZOU Bin,YANG Yu,LUO Ying-quan(Department of Cardiology,the First Hospital of Changsha,Changsha 410005,Hunan,China) |
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| Abstract: | Objective To explore the expression of P-VDGFR mRNA and proteinic level in hippocampus of rabbit with chronic intermittent hypoxia(CIH),and to analyze their clinical significance.Methods Twenty-four male rabbits were divided into blank control group,experimental group,and air mimic control group.Immunohistochemistry was used to examine the expression of hypoxia inducible factor-1alpha(HIF-1alpha)and inducible nitric oxide synthase(NOS-2)in the myocardial cells.Enzyme-linked immunosorbent assay(ELISA)was use... |
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| Keywords: | Chronic intermittent hypoxia Vascular endothelial growth factor(VEGF) Phosphorylation Hippocampus |
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