Stability of multiple-locus variable-number tandem repeats in Salmonella enterica serovar typhimurium |
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Authors: | Hopkins K L Maguire C Best E Liebana E Threlfall E J |
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Affiliation: | Laboratory of Enteric Pathogens, Health Protection Agency Centre for Infections, London, United Kingdom. katie.hopkins@hpa.org.uk |
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Abstract: | Variable-number tandem repeats (VNTRs) may evolve so rapidly that multiple profiles emerge during an outbreak. A total of 190 isolates from eight Salmonella enterica serovar Typhimurium outbreaks and 15 isolates from seven patients were analyzed by pulsed-field gel electrophoresis and VNTR typing. Small changes in loci were noted; otherwise, the VNTR profiles were stable during the course of the outbreaks. |
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