中药醋泡联合联苯苄唑乳膏治疗足癣疗效观察

将本院375例足癣患者,用随机表法随机分为治疗组（196例）和对照组（179例）,治疗组予中药醋泡联合1%联苯苄唑乳膏治疗,对照组仅外用1%联苯苄唑乳膏.以临床症状、体征评分及真菌学检测评估疗效,并记录不良反应.停药2周后,治疗组与对照组痊愈率分别为45.41%（89/196）和34.08%（61/179）,有效率分别为77.04%（151/196）和61.45%（110/179）,两组差异有统计学意义（P＜0.05）.两组真菌清除率和局部不良反应发生率的差异无统计学意义（P＞0.05）.

Efficacies and safety of traditional Chinese medicine plus bifonazole cream for tinea pedis patients

To evaluate the efficacy and safety of traditional Chinese medicine plus bifonazole 1% cream in the treatment of tinea pedis. A total of 375 patients with tinea pedis were randomly assigned to receive traditional Chinese medicine plus bifonazole 1% cream （ treatment group, n = 196） or bifonazole 1% cream alone （control group, n = 179）. Efficacy was estimated in terms of mycological care, total clinical sign and symptom scores. And adverse reactions were also recorded. The results showed that, at Week 2 post-treatment, the cure rate was 45.41% （89/196） and effective rate 77. 04% （151/196） in combination group versus 34. 08% （61/179） and 61.45% （110/179） in control group. There was significant inter- group difference （P 〈 0. 05）. The mycological effective rate of two groups was 84. 18% vs. 77.65% and the local adverse reaction rate 6. 12% vs. 2. 79%. There was no statistically significant difference （P 〉 0. 05）.