产后DIC综合征患者大量输血急救的可行性及安全性分析

目的探讨产后DIC综合征患者大量输血急救的可行性及安全性。方法选择2008年12月至2013年5月我院收治的20例产后DIC综合征患者作为观察对象,患者确诊DIC综合征后,立即吸氧,开通静脉通路,20例患者均输血液制品,11例患者输新鲜冷冻血浆+红细胞悬液,4例患者输新鲜全血与冰冻血浆,冷沉淀及血小板,6例患者输纤维蛋白原。观察大量输血急救的效果。结果 20例产后DIC综合征患者经输血后,15例救治成功,成功率为75.0%,5例救治无效死亡。输血后,患者PT、APTT、TT时间均较输血前明显缩短,差异有统计学意义(P<0.05),而FIB较输血前增加,但差异无显著性(P>0.05);输血后,PLT较输血前明显改善,差异明显(P<0.05)。结论对于产后DIC综合征患者,应早期诊断,及时去除病因,大量输血是可行且安全的治疗措施。

Analysis on the Feasibility and Safety of Massive Blood in First Aid of Postpartum Patients with DIC Syndrome

Objective To study the feasibility and safety of of massive blood in first aid of postpartum patients with DIC syndrome. Methods 20 postpartum patients with DIC syndrome from December 2008 to May 2013 in our hospital were selected as study objects, with oxygen inhalation immediately in patients with DIC syndrome, opened venous access, 20 patients were transfused blood products, 11 patients with infusion of fresh frozen plasma and red blood cell suspension, 4 patients losed the fresh whole blood and frozen plasma, cryoprecipitate and platelet, fibrinogen in 6 patients.Oobserved the effect of massive transfusion inemergency. Results 20 postpartum patients with DIC syndrome treated with blood transfusion, 15 cases were successfully cured, the success rate was 75.0%,5 cases of treatment died. After blood transfusion in patients with APTT, TT, PT time were significantly shorten than before blood transfusion, the difference was statistically significant （P＆lt;0.05）, while FIB was increased than before blood transfusion, but the difference was not significant （P〈0.05）;after blood transfusion,PLT was significantly improved than before transfusion, had significant difference （P〈0.05）.Conclusion For postpartum patients with DIC syndrome, should be early diagnosis, etiology and removed in time, massive blood transfusion is feasible and safe in the treatment of measures.