细胞核变化在甲状腺乳头状腺癌病理组织学诊断中的意义

目的：认识并掌握甲状腺乳头状腺癌的诊断依据——核的改变。方法：采用光学显微镜观察分析甲状腺手术标本１ ９９７ 例。结果：确诊甲状腺乳头状腺癌７１ 例（原诊断：恶性肿瘤２９ 例，良性肿瘤及肿瘤样病变４２例）。结论：甲状腺乳头状腺癌占原发性甲状腺恶性肿瘤的首位，诊断依据为核的三大特征：即毛玻璃样核，核包涵体，核沟。

The Pathological Diagnostic Significance of Nuclear Morphology in Thyroid Paillary Adenocarcinoma

Objective: To recognize and know well in the diagnosis foundation of thyroid papillary adenocarcinoma changes of the nucleus. Methods: Analysing the pathological data of 1997's cases with thyroid specimen by the light microscope. Results: 71 cases of thyroid papillary adenocarcinoma were diagnosed (original diagnosis: malignant tumors 29 cases, benign tumors and tumor like lesions 42 cases). Conclusion: Papillary adenocarcinoma is most commonly seen in the malignant tumors of thyroid. Changes of the nucleus are responsible to be the diagnostic foundation, including (1)ground glass nuclei; (2)intranuclear cytoplasmic inclusion; (3)nuclear groove.