Targeting irradiation‐induced mitogen‐activated protein kinase activation in vitro and in an ex vivo model for human head and neck cancer期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Targeting irradiation‐induced mitogen‐activated protein kinase activation in vitro and in an ex vivo model for human head and neck cancer

Authors:	Annette Affolter MD Marie‐France Muller Katharina Sommer Albrecht Stenzinger MD Karim Zaoui MD Katja Lorenz Thomas Wolf PhD Sarika Sharma PhD Janina Wolf Sven Perner MD Klaus‐Josef Weber PhD Kolja Freier MD Peter K. Plinkert MD Wilko Weichert MD

Affiliation:	1. Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany;2. Department of Otorhinolaryngology, Head and Neck Surgery, Experimental Head and Neck Oncology, Heidelberg University Hospital, Heidelberg, Germany;3. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg University Hospital, Heidelberg, Germany;4. Pathology of the University Hospital of Luebeck and Leibniz Research Center Borstel, Luebeck and Borstel, Germany;5. Department of Radiation Oncology, Heidelberg, Germany;6. Department of Oral and Maxillofacial Surgery, Heidelberg University Hospital, Heidelberg, Germany

Abstract:

Keywords:	ex vivo model radioresistance head and neck cancer mitogen‐activated protein (MAP) kinase signaling pathway p53 mutations mitogen‐activated protein kinase (MEK) inhibitor