冠心病患者冠脉血流的变化研究

目的探讨冠心病患者冠脉血流的变化规律。方法选取2011年7月-2012年8月在宜宾市第一人民医院进行治疗的51例冠心病患者为观察组,同期进行健康体检的51名健康人员为对照组,后将两组人员的冠脉血流指标进行检测及比较。结果观察组的收缩期血流峰值、舒张期血流峰值、冠脉血流速率储备、收缩期流速时间积分及舒张期流速时间积分[(13.11±1.23)cm/s、(26.45±3.22)cm/s、2.60±0.21、2.18±0.29、8.42±1.31]均低于对照组,而观察组中NYHA分级Ⅳ级及急性心肌梗死型患者上述指标均低于其他患者(均P<0.05)。结论冠心病患者冠脉血流呈现较差的状态,对其检测有利于了解患者的疾病严重程度及心功能分级。

Study on the Changes of Coronary Blood Flow in Coronary Heart Disease

Objective To study the changes of coronary blood flow in coronary heart disease （CHD）. Methods From July 2011 to August 2012, 51 treated patients with CHD in our hospital were selected as observation group, and 51 healthy subjects undergoing physical examination at the same time as control group. Both groups were compared for the changes of coronary blood flow. Results The values of systolic peak velocity, diastolic peak velocity, coronary flow velocity reserve, systolic flow velocity time integral and diastolic flow velocity time integral [ （ 13.11±1.23 ） cm/s、 （ 26.45±3.22 ） cm/s,2. 60 ±0.21、2.18 ±0.29±8.42±1.31 ] were lower in observation group than in control group, and for patients with CHD （ NYHA grade 1V ） or acute myocardial infarction in observation group, the values of these indexes were lower than those of the other patients,P 〈 0.05, and significant difference was found between them. Conclusions Coronary blood flow is poor in patients with CHD, and detection of these indexes is beneficial to the understanding of disease severity and cardiac func- tion grading.