血脂紊乱与骨质疏松

骨质疏松是一种常见的老年病,血脂紊乱与其常相互伴随出现.研究显示,不同类型的血脂紊乱对骨质疏松的影响也不同.研究认为,高甘油三酯血症对于女性骨密度的影响存在绝经前和绝经后的差异;低密度脂蛋白-胆固醇可通过影响骨细胞分化引起骨质疏松;高密度脂蛋白-胆固醇则对骨骼起保护性作用.同时有研究认为,他汀类降脂药可以通过影响破骨细胞、成骨细胞提高骨密度.因此,研究血脂紊乱、降脂药物与骨质疏松的关系对防治骨质疏松起到一定的指导作用.

Dyslipidemia and osteoporosis

Osteoporosis is a very common disease in old people.Dyslipidemia and osteoporosis are often observed accompanying.Researches,which focus on the relationship between different types of dyslipidemia and osteoporosis,find out that various types of dyslipidemia had various influence on osteoporosis.Hypertriglyceridemia had variable effect on women's bone mineral density.LDL-C call cause osteoporosis through interfering bone cell differentiation.HDL-C had protective effect on bone.Statin,decreasing eholesterol levels in people,can also increase bone mineral density through influencing osteoclast and osteoblast.Therefore,further research of dyslipidemia,antilipidemic agent and their relationship with osteoporosis will be helpful for the prevention and treatment of osteoporosis.