| 膀胱灌注、粘膜下定期注射丝裂霉素C预防膀胱癌术后复发疗效观察 |
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| 引用本文： | 吴成璋. 膀胱灌注、粘膜下定期注射丝裂霉素C预防膀胱癌术后复发疗效观察[J]. 青海医药杂志, 2003, 33(11): 8-10 |
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| 作者姓名： | 吴成璋 |
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| 作者单位： | 青海省大通县人民医院外二科,810100 |
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| 摘 要： | 目的 :比较单纯膀胱灌注丝裂霉素C(MMC)和膀胱灌注法、定期粘膜下注射MMC预防膀胱肿瘤术后复发的疗效 ;方法 :3 7例膀胱肿瘤术后患者分为两组 ,分别接受单纯膀胱灌注MMC和膀胱灌注及定期粘膜下注射MMC治疗 ;结果 :随访 (2 4～ 3 4)个月 ,单纯膀胱灌注组 1 5例 ,复发 6例 ,占 40 % ;膀胱灌注、定期粘膜下注射组 2 2例 ,复发 4例 ,占1 8.1 8% ,两组对比差别有显著性 (P <0 .0 5) ;结论 :膀胱灌注、定期粘膜下注射MMC预防膀胱肿瘤术后复发效果满意 ,优于单纯膀胱灌注
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| 关 键 词： | 膀胱灌注 粘膜下注射 丝裂霉素C 膀胱癌 术后复发 疗效观察 |
PREVENTION OF BLADDER CARCINOMA RECURRENCE:MITOMYCIN C INJECTION AND PERFUSION |
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| Wu Chengzhang. PREVENTION OF BLADDER CARCINOMA RECURRENCE:MITOMYCIN C INJECTION AND PERFUSION[J]. Qinghai Medical Journal, 2003, 33(11): 8-10 |
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| Authors: | Wu Chengzhang |
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| Affiliation: | Wu Chengzhang The Datong People's Hospital |
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| Abstract: | Objective:To compare the effects of mitomycin C on prevention of bladder carcimoma recurrence in various treated ways.Method:A total of 37 postoperative patient with bladder carcinoma were divided into two groups in which the mitomycin C was given by intravesical perfusion or intravesical perfusion+submucosa injection (combined group) separately.The efficiency was recorded and followed up for 12 to 34 months in the two groups.Result:The recurrent rate of bladder carcinoma in intravesical perfusion group and combined group was 40.00% and 18.18% separately.There was a significant difference (P<0.05).Conclusion:The recurrent rate of bladder carcinoma could be better prevented by inravesical perfusion combined with submucosa injection therapy with mitomycin C after operation. |
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| Keywords: | Bladder carcinoma Mitomycin C Intravesical perfusion Recurrence |
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